New Antiepileptic Drugs in Neuropsychiatric Disorders – Basic Mechanisms Related to Clinical Efficacy

Landmark, Cecilie Johannessen; Johannessen, Svein I.

doi:10.1007/978-90-481-8553-5_16

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A) Comprehension Of Paradoxical Relations Between Epilepsy A1

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“…Hypothesis of hyperia also helps to explain some other questions about epileptic and psychiatric overlapping, concretely some psychopharmacological aspects shared by these two matters: 1) Why are all anticonvulsant drugs, which initially were introduced in psychiatry as mood stabilizers, are resulting useful for more and more psychiatric disorders, concretely anxiety disorder [51], positive syndrome of schizophrenia and schizophrenic-like psychosis [52], and remarkably bipolar disorder [53] [54];…”

Section: A) Comprehension Of Paradoxical Relations Between Epilepsy Amentioning

confidence: 99%

The Hypothesis of <i>Hyperia</i> from the Perspective of Neuronal Plasticity

Alvarez-Rodriguez¹

2016

OJMP

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Section: A) Comprehension Of Paradoxical Relations Between Epilepsy Amentioning

confidence: 99%

The Hypothesis of <i>Hyperia</i> from the Perspective of Neuronal Plasticity

Alvarez-Rodriguez¹

2016

OJMP

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Psychiatric Symptoms of Epileptic Nature: An Old Hypothesis in Light of Current Psychopharmacologic Advances

Alvarez-Rodriguez¹

2015

OJPsych

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This paper analyses a hypothesis according to which many positive psychiatric symptoms should be interpreted as symptoms of epileptic nature. When we first raised this proposition, almost fifteen years ago, it was inconsistent with the widespread conviction among psychiatrists that psychopharmacological drugs used to suppress psychiatric symptoms were proconvulsant. But lately, there have appeared numerous neuroscientific investigations that defend the anticonvulsant effect of most psychopharmacological drugs, hence supporting our hypothesis. We have carried out bibliographical reviews in search of the pro-or anticonvulsant role of these substances, particularly lithium, selective serotonin reuptake inhibitors, dual antidepressants, and antipsychotic drugs. These researches show abundant evidence regarding the anticonvulsant action of these substances, a fact that contributes to a better comprehension of paradoxical relationship between epilepsy and psychoses.

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New Antiepileptic Drugs in Neuropsychiatric Disorders – Basic Mechanisms Related to Clinical Efficacy

Cited by 2 publications

References 101 publications

The Hypothesis of <i>Hyperia</i> from the Perspective of Neuronal Plasticity

The Hypothesis of <i>Hyperia</i> from the Perspective of Neuronal Plasticity

Psychiatric Symptoms of Epileptic Nature: An Old Hypothesis in Light of Current Psychopharmacologic Advances

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New Antiepileptic Drugs in Neuropsychiatric Disorders – Basic Mechanisms Related to Clinical Efficacy

Cited by 2 publications

References 101 publications

The Hypothesis of &lt;i&gt;Hyperia&lt;/i&gt; from the Perspective of Neuronal Plasticity

The Hypothesis of &lt;i&gt;Hyperia&lt;/i&gt; from the Perspective of Neuronal Plasticity

Psychiatric Symptoms of Epileptic Nature: An Old Hypothesis in Light of Current Psychopharmacologic Advances

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The Hypothesis of <i>Hyperia</i> from the Perspective of Neuronal Plasticity

The Hypothesis of <i>Hyperia</i> from the Perspective of Neuronal Plasticity