New Antibacterial Agents and Their Uses

The in vitro activity of cefodizime and two comparative cephalosporins, cefuroxime and ceftriaxone were studied against respiratory pathogens. MIC90s of cefodizime were 0.06-0.512 microgram/ml for Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae. MIC50s of cefodizime for Klebsiella pneumoniae and Staphylococcus aureus isolates were 2 micrograms/ml and 8 micrograms/ml respectively. Cefuroxime and ceftriaxone at a concentration of 2 micrograms/ml and 1 microgram/ml inhibited 50% of Klebsiella pneumoniae and 50% of Staphylococcus aureus strains studied respectively. Cefodizime inhibited many of the important respiratory pathogens and can be suggested as an active antimicrobial agent for respiratory tract infections.

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New Antibacterial Agents and Their Uses

Cited by 2 publications

References 175 publications

Comparative antimicrobial activity of ceftibuten against multiply-resistant microorganisms from belgium

Comparative antimicrobial activity of ceftibuten against multiply-resistant microorganisms from belgium

In VitroEvaluation of Cefodizime, Cefuroxime, Ceftriaxone against Respiratory Pathogens

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