New and efficient technique for the synthesis of ɛ-caprolactone using KHSO5 as an oxidising agent in the presence of a phase transfer catalyst

Direct oxidation of secondary alcohol to ester by performic acid

“…[1][2][3][4] In previous reports, alcohol can be only oxidized into the corresponding aldehydes [5][6][7][8] or ketones, [9][10][11][12] and aldehydes and ketones can be further oxidized into organic acids [13][14][15][16] or esters. [17][18][19][20] In this work, an unexpected new reaction pathway, from which secondary alcohols can be directly oxidized into esters, was found. The discovery is of vital importance to organic synthesis and degradation of lignin.…”

C-scorpionate rhenium complexes and their application as catalysts in Baeyer-Villiger oxidation of ketones

“…Alternatives to the common organic solvents (e.g., ionic liquids) [19] or phase transfer systems [20] have also been attempted. Metal-free methods also exist [12,[21][22][23][24][25], where the peroxide is activated by thiourea-based organic catalysts [21], carboxylic [22] or phosphoric acids [23], enzymes [24], bisflavins [25] or in situ formed peroxy imidic acids [12].…”

“…With the aim of developing faster and greener synthetic methods, several approaches of performing the Baeyer-Villiger oxidation have been proposed [2, [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. Among them is the use of milder and more atom-efficient oxidants, such as molecular oxygen or aqueous hydrogen peroxide, recommended for economic and environmental reasons.…”

Directed evolution of phenylacetone monooxygenase as an active catalyst for the baeyer–villiger conversion of cyclohexanone to caprolactone

“…It is also the precursor of caprolactam, a widely used bulk chemical with an annual production of about 2 Mio tonnes, which is further converted to polycaprolactam [Buntara et al, 2011]. Currently, several companies manufacture e-caprolactone by the Baeyer-Villiger oxidation of cyclohexanone (1) using stoichiometric amounts of per-acetic acid or O 2 /acetaldehyde (which generates per-acetic acid in situ) [Baj et al, 2011]. A potential biocatalytic alternative is the use of a Baeyer-Villiger monooxygenase (BVMO) in an O 2 -mediated BV reaction of 1.…”