2015
DOI: 10.1590/s1516-8913201500024
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New aminoporphyrins bearing urea derivative substituents: synthesis, characterization, antibacterial and antifungal activity

Abstract: This work studied the synthesis of 5,10,15-tris(4-aminophenyl)-20-(N,N-dialkyl/diaryl-N-phenylurea)

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Cited by 21 publications
(6 citation statements)
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References 50 publications
(39 reference statements)
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“…According to the results these complexes produced diameters of zones of inhibition between 15 mm and 22 mm against C. albicans and between 10 mm and 19 mm against A. fumigatus. Moreover, our complexes are slightly more active than Mn(III) and Co(II)-based porphyrins derivatives reported by Karimipour et al (A. fumigatus between 9 mm and 11 mm) [82] but remain in the same principles explaining the activity increase for the metal complexes [83][84][85]. According to the Overtone's concept for cell permeability [83,84] and due to the liphophilicity as an important factor in controling the antifungal activity , the lipid membrane surrounding the cell, favours the passage of only the lipid-soluble materials.…”
Section: Antifungal Activitycontrasting
confidence: 49%
“…According to the results these complexes produced diameters of zones of inhibition between 15 mm and 22 mm against C. albicans and between 10 mm and 19 mm against A. fumigatus. Moreover, our complexes are slightly more active than Mn(III) and Co(II)-based porphyrins derivatives reported by Karimipour et al (A. fumigatus between 9 mm and 11 mm) [82] but remain in the same principles explaining the activity increase for the metal complexes [83][84][85]. According to the Overtone's concept for cell permeability [83,84] and due to the liphophilicity as an important factor in controling the antifungal activity , the lipid membrane surrounding the cell, favours the passage of only the lipid-soluble materials.…”
Section: Antifungal Activitycontrasting
confidence: 49%
“…That can only occur when 1,4-PDI becomes self-polymerized at the high-RH condition. Figure portrays the continuous increase of absorbance as a function of MLD cycles at 10 ± 2% RH of the reaction chamber, indicating stepwise film growth. ,, Stepwise film growth at 10 ± 2% RH shows almost similar tends with 5 ± 2% RH condition (Figure S8a). However, limiting film growth was observed in a high-RH condition (Figure S8b).…”
Section: Resultsmentioning
confidence: 83%
“…In recent years a great deal of research has been devoted to the preparation of entities capable of inhibiting the activities of fungi [15][16][17]. Notably, the past decade has witnessed intense research devoted to the antifungal activities of porphyrin species [18][19][20].…”
Section: Introductionmentioning
confidence: 99%