New 1,3,4-Triaza-3H-indene Derivatives in Theoretical, Experimental and biological Studies
Younes Ouzidan,
Mohammed-Yassin Hjouji,
Baraa Hafez
et al.
Abstract:6-Bromo-2-phenyl-1,3,4-triazaindan under solid-liquid catalysis-transfer-phase(CTP) environment, pyridine interacts with a number of halogenated derivatives to produce the anticipated regioisomer molecules 2a and 2b. Besides, the reaction of compound (1) with bis(2-chloroethyl) amine results in the corresponding isoxazolidin-2-one derivatives (3a) and (3b) at a satisfactory yield. The synthesized compounds are confirmed by X-ray diffraction, spectral techniques (1H NMR, 13C NMR). Then, 1,3,4-Triaza-3H-indene d… Show more
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