Nevus Sebaceus of Jadassohn

Lentz, Conrad L.; Altman, Jules; Mopper, Coleman

doi:10.1001/archderm.1968.01610090066009

Cited by 17 publications

(3 citation statements)

References 6 publications

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“…There are certain interesting reports in which no ocular or neurologic deficits were seen even though the naevus sebaceous was extensive (6) and another instance in which naevus sebaceous was associated with dermoid pannus of the eye and areas of scalp alopecia that overlay a haemangioma (7). In the light of these reports and our case, it appears that naevus sebaceous syndrome may present as forme fruste.…”

Section: Discussionmentioning

confidence: 99%

Naevus Sebaceous Associated With Ocular Dermolipoma

Sehgal

Ramesh

Ghorpade

1984

The Journal of Dermatology

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Section: Discussionmentioning

confidence: 99%

Naevus Sebaceous Associated With Ocular Dermolipoma

Sehgal

Ramesh

Ghorpade

1984

The Journal of Dermatology

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“…Nevus sebaceous (NS) is a common congenital hamartoma developing mainly on the scalp and face, as a single lesion1-4. It involves proliferative changes of the sebaceous glands, sweat glands, and the hair follicles.…”

Section: Introductionmentioning

confidence: 99%

Multiple Nevus Sebaceous Occurring on the Scalp and on the Contralateral Side of the Face

Geun

Kim

et al. 2011

Ann Dermatol

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“…Rare cases are associated with systemic abnormalities such as seizures, mental retardation or defects in visual fields. [62][63][64][65][66][67] …”

Section: Introduction and Clinical Featuresmentioning

confidence: 99%

Malignant adnexal neoplasms

2006

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Malignant cutaneous adnexal neoplasms are one of the most challenging areas of dermatopathology. Tumors of the pilosebaceous apparatus can occur as single-lineage neoplasms or may manifest as complex proliferations with multilineal differentiation patterns including not only the germinative component of the hair bulb, the inner or outer root sheath epithelium and the sebaceous gland and duct, but also the sweat duct components that relate to the apocrine secretory apparatus which empties into the follicle near the follicular bulge. Eccrine and apocrine neoplasms present a bewildering array of morphologies, which often defy precise classification. The purpose of this review is to discuss in detail the malignant neoplasms of the cutaneous adnexae and their benign and prognostically indeterminate mimics. Modern Pathology (2006) 19, S93-S126. doi:10.1038/modpathol.3800511Keywords: eccrine carcinoma; sebaceous neoplasia Malignant tumors of the pilosebaceous apparatus, their mimics and precursors IntroductionTumors of the pilosebaceous unit can occur in isolation or in combination with complex proliferations showing multilineal differentiation patterns encompassing those of sweat ducts, epidermis and stroma with its varied components. In this review, we will focus upon the malignant adnexal proliferations, considering benign entities mainly insofar as they impact the diagnostic approach to adnexal carcinoma. We will first turn to the malignant sebaceous neoplasms, their precursors and their mimics. Sebaceous adenoma Clinical FeaturesThe sebaceous adenoma is a benign neoplasm that manifests clinically as a pale yellow nodular lesion, typically of the face, that expresses itself clinically after the age of 50. Tumors range in size from o1 to 45 cm. [1][2][3][4][5][6] These lesions are associated with the Muir-Torre syndrome, comprising the coexpression of cutaneous neoplasms, including those of sebaceous type with well-differentiated squamous epithelial neoplasms, and visceral malignancies, including carcinomas of the breast, ovary, gastrointestinal tract and larynx. [7][8][9][10][11][12][13][14] An occasional patient may manifest a malignant lymphoma of nodal or extranodal type. 10,12,14 Sebaceous neoplasms in the setting of Muir-Torre syndrome are often difficult to classify, showing overlap features between all of the prototypic forms of sebaceous neoplasm ranging from hyperplasia to carcinoma. 13 HistologyThe prototypic sebaceous adenoma manifests 1-2 layers of germinitive cells which mature to form central sebocytes, and have an architecture comprising a sharply circumscribed sebaceous lobule surrounded by a compressed pseudocapsule of dermal stroma ( Figure 1a). The overlying epidermis may be attenuated, but sometimes forms a collarette around the peripheral aspect of the neoplasm. Unlike sebaceous hyperplasia, occasional mitoses may be seen in the lobules of a sebaceous adenoma and in concert with this nucleoli may be somewhat prominent, but the pleomorphism, hyperchromasia and individual cell necrosis of the se...

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Nevus Sebaceus of Jadassohn

Cited by 17 publications

References 6 publications

Naevus Sebaceous Associated With Ocular Dermolipoma

Naevus Sebaceous Associated With Ocular Dermolipoma

Multiple Nevus Sebaceous Occurring on the Scalp and on the Contralateral Side of the Face

Malignant adnexal neoplasms

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