Nevus sebaceus: a clinicopathological study of 168 cases and review of the literature

Kamyab‐Hesari, Kambiz; Hassan, Sk. Sarif; Jahan, Shahin; Aghazadeh, Nessa; Hejazi, Pardis; Azizpour, Arghavan; Goodarzi, Azadeh

doi:10.1111/ijd.12845

Cited by 50 publications

(57 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It represents a benign hamartoma of the skin that combines a variety of epidermal and adnexal abnormalities. Samples of nevus sebaceus in children invariably contain primitive hair follicles and often show epidermal alterations such as acanthosis, spongiosis, and papillomatosis . Hyperplastic sebaceous glands occur later in life but ectopic apocrine glands can also be found in children .…”

Section: Discussionmentioning

confidence: 99%

“…Samples of nevus sebaceus in children invariably contain primitive hair follicles and often show epidermal alterations such as acanthosis, spongiosis, and papillomatosis . Hyperplastic sebaceous glands occur later in life but ectopic apocrine glands can also be found in children . Rare differential diagnoses of focal congenital hair loss include the benign non‐scarring alopecias congenital triangular alopecia and congenital alopecia areata.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Aplasia cutis congenita of the scalp: Histopathologic features and clinicopathologic correlation in a case series

2020

View full text Add to dashboard Cite

Background: Aplasia cutis congenita (ACC) is a rare and heterogeneous disorder characterized by congenital absence of skin. The scalp is the most commonly affected site and lesions may overlie deeper ectodermal abnormalities. The exact etiology is still unknown, and histopathologic features are poorly defined.Methods: A series of 10 cases from nine patients was analyzed to characterize the clinicopathologic spectrum and age-related changes of ACC of the scalp. Hematoxylin and eosin, S100, Elastica van Gieson, and Weigert elastic stains were performed, and clinical information was retrieved from archived medical files.Results: Patient ages ranged from 1 day to 39 years (median 57 months). All cases resembled deep-reaching scars with almost complete loss of all adnexal structures.Isolated residual hair follicles were present in 8/10 and sweat glands and ducts in 2/10 cases. The subcutis was thinned or absent. Elastic fibers were always more fragmented than in normal tissue, and the thickness and density increased over time.There was no gain of adnexal structures with increasing age. Conclusions: ACC represents a congenital scarring alopecia with permanent loss of skin appendages. Histopathologic changes resemble a deep-reaching scar with fragmented elastic fibers and differentiate ACC from all other forms of non-traumatic congenital alopecias. K E Y W O R D S aplasia cutis congenita, cicatricial alopecia, congenital scalp defect, ectodermal dysplasia, elastic fibers

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Aplasia cutis congenita of the scalp: Histopathologic features and clinicopathologic correlation in a case series

2020

View full text Add to dashboard Cite

show abstract

“…Tumoral transformation can occur over time, and more than 40 types of secondary tumors have been described, found in 13–18.9% of the analyzed specimens. These tumors occur in less than 2% of the children with sebaceous nevi …”

Section: Discussionmentioning

confidence: 99%

“…These tumors occur in less than 2% of the children with sebaceous nevi. 9,10 Sebaceous nevi have long been considered premalignant lesions whose transformation occurred in 19-21% of the cases. 11 In reality, malignant tumors are much less frequent and only occur in 0.8-3.5% of cases and almost always in adult patients.…”

Section: Discussionmentioning

confidence: 99%

Syndromic sebaceous nevus: current findings

et al. 2018

View full text Add to dashboard Cite

show abstract

“…It occurs most commonly on the head and neck while similar lesions elsewhere on the body are termed verrucous epidermal nevi. It often presents at birth with an incidence of 0.5-1% [85]. The characteristic clinical feature is a well-circumscribed, flesh-coloured, bald patch on the scalp at birth.…”

Section: Nevus Sebaceousmentioning

confidence: 99%

Infections, Infestations and Neoplasms of the Scalp

Canpolat¹

2017

Hair and Scalp Disorders

View full text Add to dashboard Cite

This chapter reviews common cutaneous infections, infestations, and neoplasms of the scalp. Infections of the scalp are subdivided into three major groups. The most seen are: (1) Bacterial: Folliculitis, folliculitis decalvans, tufted hair folliculitis and acne keloidalis nuchae. (2) Fungal: Tinea capitis, favus and kerion celsi. (3) Protozoal: Syphilitic alopecia. Pediculosis capitis is the most common worldwide infestation of the scalp. The neoplasms of the scalp are large group of different diseases due to arising different origin. In the following section, trichilemmal cyst, proliferating trichilemmal cyst, nevus sebaceous and cylindroma are discussed in detail.

show abstract

Nevus sebaceus: a clinicopathological study of 168 cases and review of the literature

Abstract: Development of malignancies in sebaceus nevi is a rare phenomenon, and decision for excision of the lesion should be made after thorough evaluation of the pros and cons.

Cited by 50 publications

References 30 publications

Aplasia cutis congenita of the scalp: Histopathologic features and clinicopathologic correlation in a case series

Aplasia cutis congenita of the scalp: Histopathologic features and clinicopathologic correlation in a case series

Syndromic sebaceous nevus: current findings

Infections, Infestations and Neoplasms of the Scalp

Contact Info

Product

Resources

About