2015
DOI: 10.1111/ijd.12845
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Nevus sebaceus: a clinicopathological study of 168 cases and review of the literature

Abstract: Development of malignancies in sebaceus nevi is a rare phenomenon, and decision for excision of the lesion should be made after thorough evaluation of the pros and cons.

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Cited by 46 publications
(47 citation statements)
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References 30 publications
(42 reference statements)
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“…It represents a benign hamartoma of the skin that combines a variety of epidermal and adnexal abnormalities. Samples of nevus sebaceus in children invariably contain primitive hair follicles and often show epidermal alterations such as acanthosis, spongiosis, and papillomatosis . Hyperplastic sebaceous glands occur later in life but ectopic apocrine glands can also be found in children .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…It represents a benign hamartoma of the skin that combines a variety of epidermal and adnexal abnormalities. Samples of nevus sebaceus in children invariably contain primitive hair follicles and often show epidermal alterations such as acanthosis, spongiosis, and papillomatosis . Hyperplastic sebaceous glands occur later in life but ectopic apocrine glands can also be found in children .…”
Section: Discussionmentioning
confidence: 99%
“…Samples of nevus sebaceus in children invariably contain primitive hair follicles and often show epidermal alterations such as acanthosis, spongiosis, and papillomatosis . Hyperplastic sebaceous glands occur later in life but ectopic apocrine glands can also be found in children . Rare differential diagnoses of focal congenital hair loss include the benign non‐scarring alopecias congenital triangular alopecia and congenital alopecia areata.…”
Section: Discussionmentioning
confidence: 99%
“…Tumoral transformation can occur over time, and more than 40 types of secondary tumors have been described, found in 13–18.9% of the analyzed specimens. These tumors occur in less than 2% of the children with sebaceous nevi …”
Section: Discussionmentioning
confidence: 99%
“…These tumors occur in less than 2% of the children with sebaceous nevi. 9,10 Sebaceous nevi have long been considered premalignant lesions whose transformation occurred in 19-21% of the cases. 11 In reality, malignant tumors are much less frequent and only occur in 0.8-3.5% of cases and almost always in adult patients.…”
Section: Discussionmentioning
confidence: 99%
“…It occurs most commonly on the head and neck while similar lesions elsewhere on the body are termed verrucous epidermal nevi. It often presents at birth with an incidence of 0.5-1% [85]. The characteristic clinical feature is a well-circumscribed, flesh-coloured, bald patch on the scalp at birth.…”
Section: Nevus Sebaceousmentioning
confidence: 99%