Nevus lipomatosus cutaneous superficialis: A report of two cases

Nevus lipomatosis cutaneous superficialis – A rare hamartoma

“…5 The clinical differential diagnoses are varied, that includes plexiform neurofibroma, smooth muscle hamartoma, nevus sebaceous, skin tag, and leiomyoma cutis. 10 These were ruled out histopathologically. Histological differentials include focal dermal hypoplasia (Goltz syndrome), lipofibromas, and giant acrochordons with fat herniation.…”

Nevus Lipomatosus Superficialis on the Left Proximal Arm

“…The classical type is usually present at birth or appears within the first two decades of life [ 3 ]. Typically, the classical type presents as asymptomatic, multiple, soft, yellowish or skin-colored, sessile or pedunculated, papules or nodules, often coalescing into plaques whose surface may be smooth, wrinkled, or cerebriform or have a peau d'orange appearance that are present in a linear, zosteriform, or segmental pattern [ 3 , 7 ]. Sites of predilection include the pelvic girdle, gluteal region, lower trunk, and upper thigh [ 3 , 7 ].…”

“…The solitary type, on the other hand, often appears between the third and sixth decade of life and typically presents as an asymptomatic, solitary, yellowish to skin-colored, dome-shaped or sessile papule or nodule, as is illustrated in the present case [ 7 ]. The lesion has no predilection for any particular site and can develop anywhere on the body, including the scalp, neck, face, eyelid, nose, knee, axilla, arm, scrotum, vulva, and clitoris [ 3 , 7 – 11 ]. The occurrence on the arm has been rarely reported and a perusal of the literature revealed only one case.…”

Nevus Lipomatosus Cutaneous Superficialis of Hoffmann and Zurhelle Type – A Rare Case Report

“…Other treatment modalities with variable rates of success include Intralesional sodium deoxycholate (24 mg/mL) followed by intralesional phosphatidylcholine (50 mg/mL) has been reported to cause clinical and histological resolution but post-injection erythema, post-inflammatory pigmentation and scarring have been observed. [18] The detergent action of sodium deoxycholate causes fat cell destruction and the released fatty acids are emulsified by phosphatidylcholine.…”

“…[18] NLCS is a rare benign hamartomatous skin condition characterised by the presence of mature ectopic adipocytes in the dermis. [7] [19] The features described by Hoffman and Zurhelle such as multiple soft skin coloured, cerebriform papules and nodules coalesce into plaques were seen in our case.…”