Nevus depigmentosus treated with suction blister grafting: Follow-up after 10 years

Abstract

Nevus depigmentosus is a congenital hypomelanotic condition for which no effective treatments are available. The hypopigmentation is permanent and enlarges in proportion with growth in the person. Here, I report a patient of nevus depigmentosus on whom we performed suction blister grafting and the resultant pigmentation was satisfactory even at a follow-up after 10 years.

Is blister grafting an acceptable answer to treating nevus depigmentosus?

“…Conventional surgical modalities used in the treatment of vitiligo, like punch grafting or melanocyte keratinocyte transplantation procedures, may not be effective in treating ND as the whole area needs to be covered with the epidermal sheeting . There are very few reports on the surgical management of ND, probably in part due to the benign nature . We find that we were able to achieve near normal, uniform, and acceptable pigmentation with suction blister grafting technique for ND.…”

“…2 There are very few reports on the surgical management of ND, probably in part due to the benign nature. [3][4][5] We find that we were able to achieve near normal, uniform, and acceptable pigmentation with suction blister grafting technique for ND. Somesh et al, have reported the use of suction blister grafting for ND and although they were able to demonstrate repigmentation, one of the complications noted was intergraft depigmentation.…”

Nevus depigmentosus: review of a mark of distinction

“…Studies of 308‐nm xenon chloride excimer laser show high recurrence rates . Suction blister grafting was effective in a few patients . Melanocyte‐keratinocyte transplantation has shown mixed results .…”

“…47,48 Suction blister grafting was effective in a few patients. 45 Melanocyte-keratinocyte transplantation has shown mixed results. 8 Recurrence of ND is common after treatment with epidermal skin grafts.…”

“…Treatment is mainly for aesthetics . Various therapeutic modalities, such as cosmetic camouflage, psoralen, and ultraviolet A radiation (PUVA) therapy, excimer laser therapy, suction blister grafting, and melanocyte‐keratinocyte transplant grafting have been attempted. Cosmetic camouflage using water‐resistant corrective makeup is a noninvasive, affordable, and effective long‐term treatment method for many hypopigmentary disorders, including ND .…”