Nevus comedonicus along<i>Blaschko′s lines</i>

Bhagwat, Pradeep Vittal; Tophakhane, RS; Rathod, RM; Tonita, Noronha M; Naidu, Varna

doi:10.4103/0378-6323.51252

Cited by 12 publications

(17 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…6 Blaschko çizgilerini takip ettiği de belirtilmiştir. 7 Komedonal lezyonlar genellikle asemptomatik olup sadece kozmetik problemlere yol açmaktadır. Bazen lezyonun inflamasyonu sonrası fistüller, sinüsler ve şiddetli skarlar gelişebilmektedir.…”

Section: Discussionunclassified

“…Skalp, palmar yüzey ve glans peniste de daha nadir olarak izlenebilmektedir. [7][8][9] NK'nin patofizyolojisi tam olarak anlaşılama-mıştır. Somatik mutasyon sonucu pilosebase ünitin mezodermal bölümünde gelişim bozukluğu meydana gelmekte, bunun sonucunda terminal kıl ve sebase gland tam olarak gelişememekte, fakat pilosebase ünit keratin oluşturabilmektedir.…”

Section: Discussionunclassified

“…NK'ye katarakt gibi göz hastalıkları, skolyoz, fused vertebra, spina bifida, zihinsel gelişimin gecikmesi, nöbetler, parezi, korpus kallozum disgenezisi, elektroensefalografik anormallikler gibi nörolojik problemler, beşinci parmağın yokluğu, polisindaktili, klinodaktili gibi iskelet anormallikleri, oligodonti, iktiyoz, lökoderma, liken striatus, linear morfea, Sturge Weber sendromu, hemanjiyom, inverse akne gibi dermatolojik problemler ve trikoepitelyoma, pilar kılıf tümörü, keratoakantoma, siringokistadenoma papilliferum, hidradenoma papilliferum gibi epitelyal tümörler eşlik edebilmekte, ayrıca çok nadiren bazal hücreli karsinom, skuamöz hücreli karsinom da görülebil-mektedir. 3,7 Üç olgumuzda iskelet, göz, santral sinir sistemi ve deri patolojisi saptanmamıştır; yalnızca üçüncü olguda doğuştan beri olan konjonktivada melanositik nevüs mevcudiyeti gözlenmiş, göz hastalıkları tarafından izlem önerilmiştir.…”

Section: Discussionunclassified

See 2 more Smart Citations

Nevus Comedonicus: Four Case Report

Acer¹,

Erdoğan²,

Tad³

2017

Turkiye Klinikleri J Dermatol

View full text Add to dashboard Cite

Section: Discussionunclassified

See 1 more Smart Citation

Nevus Comedonicus: Four Case Report

Acer¹,

Erdoğan²,

Tad³

2017

Turkiye Klinikleri J Dermatol

View full text Add to dashboard Cite

“…Nevus comedonicus is an uncommon developmental anomaly which usually appears as clusters of follicular orifices containing horny keratin plugs with a linear, nevoid, or Blaschkoid distribution 1,2 . Nevus comedonicus is reportedly considered as a hamartoma derived from abnormal development of the mesodermal component of the pilosebaceous unit, an epidermal nevus involving the hair follicle, or an appendageal nevus of the sweat ducts 3–8 .…”

mentioning

confidence: 99%

Ultrastructural features of nevus comedonicus

Cho¹,

Bang²

2011

Int J Dermatology

View full text Add to dashboard Cite

“…They may be distributed in a linear, interrupted, unilateral or bilateral pattern and sometimes follow the lines of Blaschko. 3,4 There is no sex or racial predilection. It may develop inflammatory acnelike lesions which can lead to cysts, recurrent bacterial infections, abscesses and scarring.…”

Section: Introductionmentioning

confidence: 99%

Multi-dermatomal unilateral nevus comedonicus along the lines of Blaschko: a rare presentation

Varma

Bhargava

2017

Int J Res Dermatol

View full text Add to dashboard Cite

<p>Nevus comedonicus is a rare skin disorder due to defect in development of hair follicle presenting as groups of closely set, dilated follicular openings with dark keratin plugs resembling comedones. The lesions may be distributed in a linear, interrupted, unilateral or bilateral pattern and sometimes follow the lines of Blaschko. It may develop inflammatory acne-like lesions leading to cysts, abscesses and scarring. A 36 year-old woman presented with multiple pits on left half of the body involving the face, upper limb, shoulder, back and buttock since the age of 4 years. She also had a painful swelling over the back. There was no history of cranial, skeletal or ocular involvement. Physical examination revealed multiple circular honeycomb-type pitted scars sized from 0.1×0.1 to 0.5×0.5 mm present unilaterally along lines of Blaschko in an interrupted pattern over the left half of the body as mentioned above. Among these pitted scars few scattered comedones were present with interfollicular normal skin. There was an abscess along the margin of one of the lesions over the back which was tender, indurated and with local rise of temperature. Histopathological examination revealed deep, wide invagination of acanthotic epidermis, filled with concentric lamellae of keratin. Hair shafts were occasionally seen in the dermis, below the lower part of invagination. Based on clinical and histopathological picture a diagnosis of nevus comedonicus was made. She was treated with topical tretinoin and oral retinoids without much improvement. Nevus comedonicus in itself is a rare epidermal nevus, its multi-dermatomal unilateral distribution along the lines of Blaschko is even rarer.</p>

show abstract

Nevus comedonicus alongBlaschko′s lines

Cited by 12 publications

References 4 publications

Nevus Comedonicus: Four Case Report

Nevus Comedonicus: Four Case Report

Ultrastructural features of nevus comedonicus

Multi-dermatomal unilateral nevus comedonicus along the lines of Blaschko: a rare presentation

Contact Info

Product

Resources

About