Nevoid hypertrichosis, diffuse lipoatrophy and epidermal nevus: a new syndrome?

Abstract

Therefore, we believe that these treatment modalities may have played a role in the development of KS beneath the cutaneous horn in our patient.In conclusion, KS should be considered in the differential diagnosis of lesions at the base of cutaneous horns, especially when located on the lower extremities.

Patch of increased hair growth

“…Hormonal changes during puberty could influence the expression of this mosaicism and explain the cases which arise at a later age. The association with other cutaneous diseases that show a similar segmental pattern, such as epidermal nevi or hypomelanosis of Ito, may put NH mosaic pattern within a possible twin spot phenomenon 1,3 . NH can be unfrequently associated with systemic disorders, in particular, ocular and neurological malformation, lipoatrophy and skeletal abnormalities 1–3 and recently it has been proposed as a diagnostic marker of Happle–Tinschert syndrome 4 .…”