Nevoid basal cell carcinoma syndrome: a 40‐year study in the South African population

Titinchi, Fadi; Cj, Nortjé; Parker, M.E.; Rensburg, Leon Janse van

doi:10.1111/j.1600-0714.2012.01188.x

Cited by 13 publications

(8 citation statements)

References 21 publications

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“…The literature reports wide variation in the incidence of KCOTs in NBCCS patients ranging from 62%[ 47 ] to 100%. [ 48 49 50 ] This association has been found to be 100% in our case series. Usually, multiple keratocysts are found in NBCCS ranging from 1 to 30 in number, average being 5.…”

Section: Discussionsupporting

confidence: 64%

“…[ 3 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 ] The frequency of findings in these patients in Indian literature combined with 5 patients in our case series was then compared with studies in different parts of the world and is presented in Table 5 . [ 43 44 45 46 47 48 49 50 51 ]…”

Section: Methodsmentioning

confidence: 99%

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Gorlin–Goltz syndrome: A case series of 5 patients in North Indian population with comparative analysis of literature

2015

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Objective:In Indian scenario, Gorlin–Goltz syndrome (nevoid basal cell carcinoma syndrome [NBCCS]) has been rarely reported. The clinical, radiological, and histopathological findings and major and minor criteria in five cases of NBCCS in North Indian population have been presented along with a discussion of the role of gene mutation analysis in early diagnosis of syndrome.Materials and Methods:The diagnostic findings of Gorlin–Goltz syndrome in 5 patients were compared with other reports in Indian population and with reports of this syndrome in other parts of the world.Results:The most common features seen were keratocystic odontogenic tumors (100%), calcifications of falx cerebri (60%), palmar-plantar pits (80%), rib anomalies (80%), macroencephaly (60%), ocular hypertelorism (80%), and frontal bossing (60%) in our series. Retained deciduous teeth seen in 80% patients whose association has not been previously reported has been presented. None of our patients had basal cell carcinoma, syndactyly or polydactyly, pectus deformity, bridging of sella turcica, pigmented nevi, or family history of this syndrome in contrast to such findings in other Indian patients. Medulloblastoma has not been reported in any Indian patient so far compared to this finding in other studies conducted worldwide.Conclusions:Combining the features of 48 patients in 38 cases of NBCCS being published in Indian literature with five cases of our series and on comparison with other studies in the world, a wide disparity in different ethnic groups and a wide variation in presentation of syndrome within the same population is suggested.

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Section: Discussionsupporting

confidence: 64%

Section: Methodsmentioning

confidence: 99%

Gorlin–Goltz syndrome: A case series of 5 patients in North Indian population with comparative analysis of literature

2015

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“…These data support the previous findings showing that these cysts are diagnosed at a younger age-according to Jung et al, 17 in the second decade of life-in patients with NBCCS. 18 OKCs can recur long after treatment has been performed. Oikarinen et al 19 reported recurrences 14 to 21 years after treatment.…”

Section: Discussionmentioning

confidence: 99%

Does Surgical Fragmentation of Odontogenic Keratocystic Capsule Interfere With the Recurrence Rate?

Daroit

Vieira

Visioli

et al. 2018

Journal of Oral and Maxillofacial Surgery

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“…Keratocystic odontogenic tumor also known as OKC includes about 11 % of all cysts of jaws [9] and occurs in more than 75 % of Gorlin's syndrome patients [6,10,11]. The prevalent age is second and third decades and it has a slight male tendency.…”

Section: Discussionmentioning

confidence: 99%

Conservative Treatment Protocol of Keratocystic Odontogenic Tumor: Report of a Case with Nevoid Basal Cell Carcinoma Syndrome and Literature Review

Hasheminia

Naemi

Naghdi

2014

J. Maxillofac. Oral Surg.

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Keratocystic odontogenic tumor (KOT) is one of the major components of nevoid basal cell carcinoma syndrome (NBCCS), which usually occurs in young ages and includes significant structures of jaws. According to high recurrence rate of KOT, there are many controversies in treatment of the lesion, especially in syndromic cases with younger ages. In current report, authors suggest a conservative protocol in the treatment of KOT in a patient with NBCCS.

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Nevoid basal cell carcinoma syndrome: a 40‐year study in the South African population

Cited by 13 publications

References 21 publications

Gorlin–Goltz syndrome: A case series of 5 patients in North Indian population with comparative analysis of literature

Gorlin–Goltz syndrome: A case series of 5 patients in North Indian population with comparative analysis of literature

Does Surgical Fragmentation of Odontogenic Keratocystic Capsule Interfere With the Recurrence Rate?

Conservative Treatment Protocol of Keratocystic Odontogenic Tumor: Report of a Case with Nevoid Basal Cell Carcinoma Syndrome and Literature Review

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