Neutrophil to lymphocyte ratio changes predict small hepatocellular carcinoma survival

Peng, Wei; Li, Chuan; Wen, Tianfu; Yan, Lvnan; Li, Bo; Wang, Wentao; Yang, Jiayin; Xu, Mingqing

doi:10.1016/j.jss.2014.05.078

Cited by 80 publications

(88 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Similar to these findings, Dan et al 14 reported that postoperative NLR change was a significant predictive factor for survival outcomes for the hepatocellular carcinoma (HCC) patients treated with radiofrequency ablation. Peng et al 15 suggested that increased NLR dynamics were a poor prognostic factor for HCC patients undergoing surgery. Therefore, in addition to the prognostic significance of preoperative NLR, postoperative NLR in the early recovery period can be the prognostic factor for patients with bladder cancer undergoing RC.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Prognostic Significance of the Early Postoperative Neutrophil-to-Lymphocyte Ratio in Patients with Urothelial Carcinoma of the Bladder Undergoing Radical Cystectomy

et al. 2015

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

“…12 Although previous studies have highlighted preoperative NLR, the dynamics of NLR after treatment can better reflect the balance between tumors and host immune responses. 14,15 Therefore, we hypothesized that posttreatment NLR also may be a significant prognostic factor that predicts the survival outcome for cancer patients.…”

mentioning

confidence: 99%

The Prognostic Significance of the Early Postoperative Neutrophil-to-Lymphocyte Ratio in Patients with Urothelial Carcinoma of the Bladder Undergoing Radical Cystectomy

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Inflammatory markers have been tested in many studies and their diagnostic value is increasing day by day. [7,8] AA is an inflammation of appendix vermiformis which is directly associated with inflammatory processes. Therefore, many inflammatory markers have been studied in AA and are still being studied.…”

Section: Discussionmentioning

confidence: 99%

Laboratory markers has many Valuable Parameters in the discrimination between acute appendicitis and renal colic

Acar

Özcan

Deliktaş

et al. 2015

Ulus Travma Acil Cerrahi Derg

View full text Add to dashboard Cite

BACKGROUND:Only one diagnostic parameter is not available for acute appendicitis. For the establishment of diagnosis, combination of medical history, clinical, laboratory tests, and radiological imaging modalities are used so as to decrease the rates of negative laparotomy and morbidity secondary to delay in diagnosis. Thepresent study aimed to determine haematological and inflammatory markers which will be used in the discrimination of acute appendicitis (AA) and renal colic which are the most frequent and indistinguishable causes of abdominal pain in patients applying to the emergency service.

show abstract

“…The change in NLR (ΔNLR) represents the balance between protumor inflammatory response and antitumor immune response after the surgical removal of the tumor, which may affect prognosis 14. Some studies have found that ΔNLR is a useful prognostic predictor in patients with hepatocellular carcinoma 14,15.…”

Section: Introductionmentioning

confidence: 99%

The postoperative neutrophil-to-lymphocyte ratio and changes in this ratio predict survival after the complete resection of stage I non-small cell lung cancer

Jin¹,

Han

Shi

et al. 2016

OTT

View full text Add to dashboard Cite

PurposeAlthough numerous studies have demonstrated associations between the preoperative neutrophil-to-lymphocyte ratio (NLR) and long-term outcomes in patients with non-small cell lung cancer (NSCLC), the prognostic significance of postoperative NLR and change in NLR (ΔNLR) is unknown for patients who underwent complete resection of stage I NSCLC. The aim of this retrospective study was to evaluate the prognostic significance of postoperative NLR and ΔNLR in 123 patients with stage I NSCLC.Patients and methodsThis retrospective study included preoperative and postoperative data of 123 patients who underwent surgical resection for stage I NSCLC. The relationship between disease-free survival (DFS), overall survival (OS), and clinicopathological factors, including NLR, lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio, and their changes, was analyzed using both univariate Kaplan–Meier and multivariate Cox regression methods.ResultsThe 5-year DFS and OS rates in our cohort were 60.16% and 67.48%, respectively. Univariate analysis revealed that age (P=0.045), smoking status (P=0.033), preoperative NLR (P=0.032), postoperative NLR (P<0.001), ΔNLR (P=0.004), and change in LMR (ΔLMR) (P=0.025) were significant predictors of DFS and that age (P=0.039), smoking status (P=0.042), postoperative NLR (P<0.001), ΔNLR (P=0.004), and ΔLMR (P=0.011) were independent predictors of OS. Multivariate analysis confirmed that postoperative NLR (hazard ratio [HR] =2.435, P=0.001) and ΔNLR (HR =2.103, P=0.012) were independent predictors of DFS and that postoperative NLR (HR =2.747, P=0.001) and ΔNLR (HR =2.052, P=0.018) were significant prognostic factors of OS.ConclusionOur study reported for the first time that postoperative NLR and ΔNLR – but not preoperative NLR – were independent prognostic factors of DFS and OS in patients with stage I NSCLC who underwent complete resection. This easily available biomarker might be helpful in individual risk assessment.

show abstract

Neutrophil to lymphocyte ratio changes predict small hepatocellular carcinoma survival

Cited by 80 publications

References 33 publications

The Prognostic Significance of the Early Postoperative Neutrophil-to-Lymphocyte Ratio in Patients with Urothelial Carcinoma of the Bladder Undergoing Radical Cystectomy

The Prognostic Significance of the Early Postoperative Neutrophil-to-Lymphocyte Ratio in Patients with Urothelial Carcinoma of the Bladder Undergoing Radical Cystectomy

Laboratory markers has many Valuable Parameters in the discrimination between acute appendicitis and renal colic

The postoperative neutrophil-to-lymphocyte ratio and changes in this ratio predict survival after the complete resection of stage I non-small cell lung cancer

Contact Info

Product

Resources

About