Neutrophil heterogeneity and aging: implications for COVID-19 and wound healing
Yi Liu,
Changlan Xiang,
Zhenni Que
et al.
Abstract:Neutrophils play a critical role in the immune response to infection and tissue injury. However, recent studies have shown that neutrophils are a heterogeneous population with distinct subtypes that differ in their functional properties. Moreover, aging can alter neutrophil function and exacerbate immune dysregulation. In this review, we discuss the concept of neutrophil heterogeneity and how it may be affected by aging. We then examine the implications of neutrophil heterogeneity and aging for COVID-19 pathog… Show more
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