Neutropenia Precautions for Children Receiving Chemotherapy or Stem Cell Transplantation for Cancer

Abstract

Infections in children and adolescents with cancer are a significant cause of morbidity and mortality, especially in those receiving chemotherapy who are neutropenic and/or immunocompromised. The aim of this article is to review existing evidence in order to provide a practice recommendation to prevent or minimize infections in neutropenic and/or immunocompromised patients receiving chemotherapy and/or stem cell transplant. Systematic reviews were undertaken and research was graded according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. A variety of interventions are implemented to reduce infections in the neutropenic and/or immunocompromised population; however, few are supported by research evidence. Existing literature should continue to be reviewed to further identify interventions that can influence positive patient outcomes and provide opportunities for individuals in the medical field to work together to improve clinical care.

Reflections on the Past Decade in Evidence-Based Practice Within the Children's Oncology Group

“…Rodgers, Withycombe, and Hockenberry (Rodgers et al, 2014). Selected EBP projects from COG (Rusch et al, 2014) and Duke University (Mize et al, 2014) were subsequently featured in a COG-led preconference workshop -"The Process of Evidence-Based Practice"-held at the APHON Annual Conference in September 2015.…”

“…Workshop attendees included two members from each EBP team (three teams from COG, two teams from APHON, and one team from Duke University School of Nursing). The 2013 COG teams presented their evidence summaries and recommendations at the COG meeting in September 2013, and the work from all teams attending the workshop was later featured in a special EBP-focused edition of the Journal of Pediatric Oncology Nursing (Conway et al, 2014; Duran et al, 2014; Fernbach et al, 2014; Mize et al, 2014; Robinson et al, 2014; Rusch et al, 2014), which was guest-edited by Drs. Rodgers, Withycombe, and Hockenberry (Rodgers et al, 2014).…”

Peran Skor Kandida Sebagai Metode Diagnostik Kandidiasis Invasif Terhadap Neutropenia Berat pada Anak dengan Keganasan

“…11 Oleh karena itu, asuhan keperawatan dan medis khusus yang dilakukan pada kelompok pasien dengan neutropenia meliputi filtrasi HEPA, cuci tangan, pemakaian masker, baju, dan penutup sepatu khusus, perawatan mulut, dan diet khusus. 12 Pemakaian antibiotik intravena pada pasien risiko tinggi yang ditentukan berdasarkan kadar interleukin-8 juga dapat dipertimbangkan pada pasien dengan febrile neutropenia. 13 Irene Ratridewi dkk: Peran skor kandida sebagai metode diagnostik kandidiasis invasif terhadap neutropenia berat dengan keganasan Hasil uji komparasi antara dua kelompok menunjukkan bahwa pada anak dengan diagnosis kandidiasis invasif yang terkonfirmasi dengan kultur darah memiliki hitung neutrofil yang lebih rendah dibandingkan dengan kelompok dengan hasil kultur negatif.…”