Abstract:5034
Introduction
Lenalidomide is approved in relapsed/refractory (rel/ref) MM based on 2 large phase III trials (Dimopoulos NEJM 2007; Weber NEJM 2007). In these trials, grade 3–4 neutropenia was common (29-41%) and was a main cause for lenalidomide (len) dose reductions despite mandated use of daily GCSF as first-step neutropenia management. Optimal management for len-induced neutropenia is unclear. At our institution, 216 patients (pts) with rel/ref MM wer… Show more
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