Abstract:India is hyperendemic to dengue virus and over 50% of the adults are seropositive but there is limited information on the association between prior dengue exposure with neutralizing antibody profiles and how this could influence virus evolution and vaccine development. In this work, we found that the dengue seropositivity increased with age and pre-existing antibody levels negatively correlated with viremia during acute phase of illness. Adults showed a higher levels of viremia which associated with lower leve… Show more
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