Neutral evolution of snoRNA Host Gene long non-coding RNA affects cell fate control
Matteo Vietri Rudan,
Kalle H. Sipilä,
Christina Philippeos
et al.
Abstract:SummaryA fundamental challenge in molecular biology is to understand how evolving genomes can acquire new functions. Several recent studies have underscored how non-conserved sequences can contribute to organismal diversification in the primate lineage1–3. Actively transcribed, non-coding parts of the genome provide a potential platform for the development of new functional sequences4, but their biological and evolutionary roles remain largely unexplored. Here we show that a set of neutrally evolving long non-… Show more
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