Neurovascular biomarkers as prognostic criteria for the formation of neurological disorders in children in the remote period

Abstract

The study established a pattern of changes in neurovascular biomarkers in children who underwent perinatal hypoxia in order to optimize the prognosis of neurological disorders in children in the long term. Materials and methods. 419 patients aged 1 to 6 months were examined, 2 age groups 1-3 and 4-6 months were identified, the physical and psychomotor development of each subject was analyzed, and groups of mild, medium and severe forms of lesion were identified; a quantitative assessment of the biochemical markers of the neurovascular component of the pathogenesis of CNS lesion was carried out with the identification of the boundaries of the formation of processes. Results. The direct dependence of changes in indicators of biochemical markers on the degree of CNS damage was established.