Neurotrophic Hypothesis of Development of Depression
A. L. Yasenyavskaya,
A. A. Tsibizova,
M. A. Samotrueva
Abstract:Currently, depression is a widespread mental disorder in modern society and is associated with significant impairments in the quality of life of patients. The review examines the main representatives of neurotrophic factors belonging to various families, in particular nerve growth factor, transforming growth factor beta, neurokines and non-neuronal factors. Neurotrophins, being large polypeptides, play an integrative role, fulfilling the signaling mission of intermediaries in a wide range of physiological proc… Show more
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