Neurotrophic and Neuroprotective Effects of Hericium erinaceus

Szućko-Kociuba, Izabela; Trzeciak-Ryczek, Alicja; Kupnicka, Patrycja; Chlubek, Dariusz

doi:10.3390/ijms242115960

Cited by 10 publications

(2 citation statements)

References 140 publications

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“…However, to the best of our knowledge, it has not been tested for use in treating SCD chronic pain [ 236 ]. H. erinaceus can regulate heat shock proteins (HSP70), which has the potential to offer beneficial health effects [ 237 ].…”

Section: Nutritional Perspectives In Sickle Cell Diseasementioning

confidence: 99%

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Sickle Cell Disease Update: New Treatments and Challenging Nutritional Interventions

Bell,

Varzakas,

Psaltopoulou

et al. 2024

Nutrients

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Sickle cell disease (SCD), a distinctive and often overlooked illness in the 21st century, is a congenital blood disorder characterized by considerable phenotypic diversity. It comprises a group of disorders, with sickle cell anemia (SCA) being the most prevalent and serious genotype. Although there have been some systematic reviews of global data, worldwide statistics regarding SCD prevalence, morbidity, and mortality remain scarce. In developed countries with a lower number of sickle cell patients, cutting-edge technologies have led to the development of new treatments. However, in developing settings where sickle cell disease (SCD) is more prevalent, medical management, rather than a cure, still relies on the use of hydroxyurea, blood transfusions, and analgesics. This is a disease that affects red blood cells, consequently affecting most organs in diverse manners. We discuss its etiology and the advent of new technologies, but the aim of this study is to understand the various types of nutrition-related studies involving individuals suffering from SCD, particularly in Africa. The interplay of the environment, food, gut microbiota, along with their respective genomes collectively known as the gut microbiome, and host metabolism is responsible for mediating host metabolic phenotypes and modulating gut microbiota. In addition, it serves the purpose of providing essential nutrients. Moreover, it engages in direct interactions with host homeostasis and the immune system, as well as indirect interactions via metabolites. Nutrition interventions and nutritional care are mechanisms for addressing increased nutrient expenditures and are important aspects of supportive management for patients with SCD. Underprivileged areas in Sub-Saharan Africa should be accompanied by efforts to define and promote of the nutritional aspects of SCD. Their importance is key to maintaining well-being and quality of life, especially because new technologies and products remain limited, while the use of native medicinal plant resources is acknowledged.

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Section: Nutritional Perspectives In Sickle Cell Diseasementioning

confidence: 99%

“…Decrease in hemoglobin polymerization rate [233] Auricularia auricular Free radical scavenging activity [235] Hericium erinaceus Regulation of heat shock proteins (HSP70) [237] Termitomyces Increase hemoglobin levels and white blood cells [238]…”

Section: Ganoderma Lucidummentioning

confidence: 99%