Abstract:BackgroundThe neurochemical background of the evolution of headache disorders, including migraine, still remains partially undiscovered. Accordingly, our aim was to further explore the neurochemical profile of Complete Freund’s adjuvant (CFA)-induced orofacial pain, involving finding the shift point regarding small molecule neurotransmitter concentrations changes vs. that of the previously characterized migraine-related neuropeptides. The investigated neurotransmitters consisted of glutamate, γ-aminobutyric ac… Show more
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