Neuroticism, stress, and rumination in anxiety and depression of people with Vitiligo: An explanatory model

Bu, Emerson Araújo Do; Santos, Vitória Medeiros dos; Lima, Kaline da Silva; Pereira, Cí­cero Roberto; Alexandre, Maria Edna Silva de; Bezerra, Viviane Alves dos Santos

doi:10.1016/j.actpsy.2022.103613

Cited by 7 publications

(9 citation statements)

References 30 publications

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“…The HAMA was developed by Hamilton in 1959 and includes 14 items ( 18 , 19 ): (I) anxiety mood; (II) tension; (III) fear; (IV) insomnia; (V) cognitive function; (VI) depression mood; (VII) somatic anxiety (muscle system symptoms); (VIII) sensory system symptoms; (IX) cardiovascular system symptoms; (X) respiratory system symptoms; (XI) gastrointestinal and digestive tract symptoms; (XII) reproductive and urinary system symptoms; (XIII) autonomic nervous system symptoms, and (XIV) behavior when talking to people. In this study, 2 trained assessors jointly evaluated patients with the HAMA through conversation and observation.…”

Section: Methodsmentioning

confidence: 99%

Association between skin disease and anxiety: a logistic analysis and prediction

Sun¹,

Ren²,

Zhang³

2023

Ann Transl Med

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Background Dermatosis has symptoms of flushing, itching, pain, and burning, which causes psychological distress in patients. Methods We collected the data of 214 patients from the Wuhan Institute of Dermatology and Venereology from January 2020 to January 2022, including age, gender, diagnosis, Hamilton Anxiety Rating Scale (HAMA), and anxiety. First, descriptive analysis and difference analysis of the included data were carried out. Second, a correlation matrix was used to exclude the confounding factors with strong collinearity. Finally, logistic regression was used to analyze and predict the risk factors of anxiety. Results In the anxiety group and nonanxiety group, eczema and generalized eczema accounted for the largest proportion, and there was no difference in the composition of the diagnosis between the 2 groups. Several related analyses proved the accuracy of the logistic model. The results showed that age had a protective effect on the anxiety of patients with skin diseases [odds ratio (OR) =0.8606 with 95% confidence interval (CI): 0.7812, 0.8987]. Neurodermatitis (OR =1.0853 with 95% CI: 1.0115, 1.2512), eczema (OR =1.1358 with 95% CI: 1.0215, 1.2129), generalized eczema (OR =1.3346 with 95% CI: 1.1212, 1.5521), and psoriasis (OR =1.3685 with 95% CI: 1.1728, 1.6215) were associated with the anxiety of patients. Prediction analysis showed that with increase of patients’ age, the likelihood of anxiety decreased. Conclusions This study demonstrated a strong correlation between skin diseases and anxiety and that the likelihood of anxiety decreases as age increases. Therefore, psychological intervention for patients with skin diseases, especially young patients, is essential.

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Section: Methodsmentioning

confidence: 99%

Association between skin disease and anxiety: a logistic analysis and prediction

Sun¹,

Ren²,

Zhang³

2023

Ann Transl Med

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“…Even behaviorists therapists themselves do not practice it in a large enough, regular, and repeated manner, perhaps because it takes more time and is more difficult to manage in this disorder than in others. It's also known that exposure can affect the disease's cognitive components, including self-deprecating ruminations (Do Bú et al, 2022). However, patients are required also, to expose themselves in a specific cognitive environment, based on their acceptance of their thoughts, emptions, needs and values (National Collaborating Centre for Mental Health, 2013).…”

Section: Management Of the Social Anxietymentioning

confidence: 99%

The Management of Social Anxiety: More Than 25 Years Later, Where are we?

ElBarazi

Meshreky

2022

Illness, Crisis & Loss

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Behavioral and cognitive therapies are today the most effective toolbox and the most evidenced-based therapy for social anxiety. The purpose of this article is to provide an overview of some of the most popular methods for treating social anxiety. A selective review of literature published between 1997 and 2022 on social anxiety management. We have found that the majority of behavioral and cognitive treatment protocols are based on the following pillars: exposure to avoided situations, cognitive restructuring, assertiveness, and social skills training, as well as decentration techniques such as getting out of self-observation and cognitive fusion. Several psychotherapists agree on some components of social anxiety management while others do not. Within these agreements and disagreements, the path to the sketch of a new model should open. We argue that some techniques may ultimately be useless, counterproductive, and time-consuming. Alter the existing models and improve them in a different way in light of the multiple information and clinical examples is much needed. We suggest reconfiguring the theoretical and clinical elements to derive a new therapeutic combination of old techniques. In this new theoretical model of social anxiety, we scrupulously suggest including the cognitive and emotional elements and opt for primacy to be given to behavioral inhibition and the role of the biological part such as amygdala.

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“…[1][2][3] Since its earliest recognition as a 'cosmetic disease', vitiligo has received increasing academic and societal attention in view of its potential for severe loss of quality of life and increased burden, coupled with its potential as a sign of autoimmune system disorders. [4][5][6] People with vitiligo often seem to have poor mental health, but the academic community remains divided. [5][6][7] Ezzedine's meta-analysis revealed a wide-ranging prevalence of psychosocial comorbidities, encompassing depression, anxiety, bipolar disorder, sleep disorders, OCD and ADHD, among vitiligo patients, with estimates spanning from 32.6% to 90.0%.…”

Section: Introductionmentioning

confidence: 99%

“…[4][5][6] People with vitiligo often seem to have poor mental health, but the academic community remains divided. [5][6][7] Ezzedine's meta-analysis revealed a wide-ranging prevalence of psychosocial comorbidities, encompassing depression, anxiety, bipolar disorder, sleep disorders, OCD and ADHD, among vitiligo patients, with estimates spanning from 32.6% to 90.0%. 5 According to another research, there are no appreciable variations in anxiety and depressive symptoms between vitiligo sufferers and healthy people using the Beck Inventory scales.…”

Section: Introductionmentioning

confidence: 99%

“…People with vitiligo often seem to have poor mental health, but the academic community remains divided 5–7 . Ezzedine's meta‐analysis revealed a wide‐ranging prevalence of psychosocial comorbidities, encompassing depression, anxiety, bipolar disorder, sleep disorders, OCD and ADHD, among vitiligo patients, with estimates spanning from 32.6% to 90.0% 5 .…”

Section: Introductionmentioning

confidence: 99%

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Exploring genetic associations between vitiligo and mental disorders using Mendelian randomization

Wang,

Yao,

Lin

et al. 2023

Experimental Dermatology

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Although a large number of existing studies have confirmed that people with vitiligo are prone to mental disorders, these observational studies may be subject to confounding factors and reverse causality, so the true causal relationship is inconclusive. We conducted a bidirectional Mendelian randomization (MR) analysis to assess the causality between vitiligo and mental disorders, namely depression, anxiety, insomnia, schizophrenia, bipolar disorder, obsessive‐compulsive disorder (OCD) and attention‐deficit hyperactivity disorder (ADHD). Summary statistics from large available genome‐wide association study (GWAS) datasets for generalized vitiligo (n = 44 266), depression (n = 173 005), anxiety (n = 17 310), insomnia (n = 386 988), schizophrenia (n = 130 644), bipolar disorder (n = 413 466), OCD (n = 9725) and ADHD (n = 225 534) were utilized. Inverse‐variance weighted (IVW), MR‐Egger and weighted median were employed to estimate causal effects. Sensitivity analysis and MR Pleiotropy Residual Sum and Outliers (MR PRESSO) were conducted to assess heterogeneity and pleiotropy, ensuring the robustness of the results. Additionally, we corrected for estimating bias that might be brought on by sample overlap using MRlap. In our findings, none of the rigorous bidirectional MR analyses uncovered a significant causal association. Even after applying the MRlap correction, the effect sizes remained statistically nonsignificant, thereby reinforcing the conclusions drawn via IVW. In summary, our genetic‐level investigation did not reveal a causal link between generalized vitiligo and mental disorders.

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Neuroticism, stress, and rumination in anxiety and depression of people with Vitiligo: An explanatory model

Cited by 7 publications

References 30 publications

Association between skin disease and anxiety: a logistic analysis and prediction

Association between skin disease and anxiety: a logistic analysis and prediction

The Management of Social Anxiety: More Than 25 Years Later, Where are we?

Exploring genetic associations between vitiligo and mental disorders using Mendelian randomization

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