Neuroticism and posttraumatic stress disorder: A Mendelian randomization analysis
Zifan You,
Shanshan Chen,
Jinsong Tang
Abstract:ObjectiveEpidemiological studies revealed an unestablished association between neuroticism and posttraumatic stress disorder (PTSD) and we conducted mendelian randomization (MR) analyses to examine whether neuroticism clusters of worry, depressed affect, and sensitivity to environmental stress and adversity (SESA) were involved in the development of PTSD.MethodWe obtained data on three neuroticism clusters, PTSD, and nine other psychiatric disorders from genome‐wide association studies summary statistics and e… Show more
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