Neurosis of the Bladder

Hunner, Guy L.

doi:10.1016/s0022-5347(17)72933-3

Cited by 16 publications

(3 citation statements)

References 3 publications

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“…Nevertheless, his description of lesions remained the gold standard for years to come. His terms changed over time: initially a “rare type of bladder ulcer”; later the “elusive ulcer” (a term coined by his colleague Thomas Cullen), while by 1930 he was calling the condition “neurosis of the bladder.”…”

Section: Guy Leroy Hunner (1868–1957)mentioning

confidence: 99%

Interstitial cystitis and the painful bladder: A brief history of nomenclature, definitions and criteria

Meijlink

2014

Int J of Urology

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“Practically every author writing on this subject has suggested a new name which only adds to the confusion and multiplication” (Kretschmer H, 1922). Despite multiple names and many definitions and classifications over the past two centuries, the medical world is no closer to discovering the cause or causes of this enigmatic bladder disorder, currently known as interstitial cystitis, bladder pain syndrome or painful bladder syndrome and hypersensitive bladder. International consensus on nomenclature, definitions and diagnosis is now essential to ensure that studies are carried out on the same basis, thereby generating meaningful data that can be relied on for further use. In our electronic age, multiple names and definitions cause confusion for researchers, clinicians and patients, even leading to the patient's diagnosis being unrecognized by authorities, resulting in refusal to reimburse treatment or provide social benefits. As the key to the puzzle lies in the patients, with all their symptoms and comorbidities, and as patients are directly affected by changes in nomenclature and definitions, patient organization representatives should be given every opportunity to participate in discussions on guidelines, taxonomy, definitions and terminology.

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Section: Guy Leroy Hunner (1868–1957)mentioning

confidence: 99%

Interstitial cystitis and the painful bladder: A brief history of nomenclature, definitions and criteria

Meijlink

2014

Int J of Urology

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“…Even though many practitioners still consider bladder ulcerations to be a sine qua non of IC, estimates of ulcerative IC range from only 5% to 20% [24,28]. At first, Hunner advocated for the resection of the ulcerated tissue, but the high recurrence rate led him to abandon this surgical approach, which he detailed in an article with the interesting title of "Neurosis of the Bladder" [59]. Actually, Hunner's ulcers are not even true ulcers but rather areas of inflamed granulation tissue that are probably better referred to as a "Hunner's patches" (see Figure 1).…”

Section: Cystoscopymentioning

confidence: 99%

Neuromodulation in Intractable Interstitial Cystitis and Related Pelvic Pain Syndromes

Brookoff

Bennett

2006

Pain Med

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Many people suffering with interstitial cystitis (IC) and related pelvic pain syndromes do not benefit from the standard medical or surgical treatments. The pathophysiology of IC bears striking similarities to a wide variety of disorders driven by neurogenic inflammation, many of which may someday be controlled through neuromodulation. Because the bladder is accessible to repeated inspection, functional monitoring, biopsy, and collection of effluents, the study of neuromodulation in IC promises to yield important insights into the successful application of neuromodulatory approaches to diseases of the pelvis and other areas. Clinical experience suggests that neuromodulation in pelvic pain syndromes can successfully normalize the motor function of the bladder and pelvic muscles, as well as their sensoria. Useful neuromodulatory approaches that have potential for the treatment of intractable IC and related syndromes, such as certain cases of chronic prostatitis and pelvic floor dysfunction, include stimulation of afferent pathways using high-frequency stimulation of sacral roots and low-frequency stimulation of motor fibers innervating pelvic floor muscles via sacral roots or the posterior tibial nerve. While the lifetime incidence of chronic pelvic pain in American women is estimated to be as high as 33%, fewer than 1% of these patients are ever seen by pain specialists. Developing neuromodulatory strategies for IC and pelvic pain may also hold promise for the effective treatment of certain syndromes involving intractable urinary retention, lower bowel disorders, or sexual dysfunction.

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“…And for the origin of the bladder neck lesion, that the thickening and sclerosis of the deep tissue of the bladder neck takes place in a nervous woman, or in other words, two factors, organic and functional, seem to be necessary, and inflammation in the mucosa and the "female prostate" are insignificant. Hunner(1930), Fols0m et a1. (1931,1943,1945), Ormond(1935), Hortolomei et ai.…”

mentioning

confidence: 99%

Pathological Study of Female Urethro-Trigonitis

Sasage

1955

Jpn. j. urol

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Neurosis of the Bladder

Cited by 16 publications

References 3 publications

Interstitial cystitis and the painful bladder: A brief history of nomenclature, definitions and criteria

Interstitial cystitis and the painful bladder: A brief history of nomenclature, definitions and criteria

Neuromodulation in Intractable Interstitial Cystitis and Related Pelvic Pain Syndromes

Pathological Study of Female Urethro-Trigonitis

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