1998
DOI: 10.1016/s0887-8994(98)00058-7
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Neuroradiologic aspects of West syndrome

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Cited by 19 publications
(12 citation statements)
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“…A study on neuroradiological aspects of infantile spasm in patients also reported normal computerized tomography (CT) in 17% and normal magnetic resonance imaging (MRI) in 18% (22), while in our study it was abnormal in3 6 %. Magnetic resonance imaging (MRI) is more informative than tomography (CT) as it demonstrates focal cortical and subcortical lesions and white matter lesions better and may also help in prognostication of motor outcome in these cases (23).…”
Section: Discussionsupporting
confidence: 44%
“…A study on neuroradiological aspects of infantile spasm in patients also reported normal computerized tomography (CT) in 17% and normal magnetic resonance imaging (MRI) in 18% (22), while in our study it was abnormal in3 6 %. Magnetic resonance imaging (MRI) is more informative than tomography (CT) as it demonstrates focal cortical and subcortical lesions and white matter lesions better and may also help in prognostication of motor outcome in these cases (23).…”
Section: Discussionsupporting
confidence: 44%
“…18 A finding unavailable in the relevant literature, however, and thus of special interest, was the presence of dysgenesis accompanying cranial MRI changes owing to rubella infection, as was confirmed by specific laboratory tests (see Figure 2). As a result of purulent or tuberculous meningitis and herpes simplex encephalitis, which have previously been reported as etiologic factors in infantile spasms, 9,10,14 porencephaly, encephalomalacia, ventricular enlargement, thalamic and putaminal lesions, and cerebellar cortical hemorraghic changes have been encountered in the cranial MRIs of our patients, in addition to calcifications attributable to intrauterine infections, as mentioned above.…”
Section: Discussionsupporting
confidence: 77%
“…[8][9][10] In addition to cranial MRI changes related to hypoxic damage in 30.1% of our patients, 7 patients in this group showed additional lesions indicating changes secondary to (possibly perinatal) hypoglycemia. Periventricular leukomalacia reflecting hypoxic damage in infants with premature delivery, a previously reported condition related to the etiology of infantile spasms, 11,12 was present in 4 cases in our patient population.…”
Section: Discussionmentioning
confidence: 93%
“…There are no class I or class II imaging studies in children with IS. Among class III and IV studies, 40–50% of patients showed clear migration abnormalities or syndromes, and 20% showed nonspecific abnormalities (e.g., atrophy) (Aydinli et al., 1998; Saltik et al., 2003). Early imaging is important to assist with etiologic differential diagnosis.…”
Section: Patient Evaluation and Diagnostic Workupmentioning
confidence: 99%