Neuropsychological Sequelae of Childhood Cancer

Hocking, Matthew C.; Alderfer, Melissa A.

doi:10.1002/9781119941033.ch15

Cited by 8 publications

(5 citation statements)

References 81 publications

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“…Impacts on IQ, verbal and nonverbal reasoning, memory, attention, processing speed, and executive functioning remain significant concerns (Hocking & Alderfer, 2012). Data from pediatric psychologists and neuropsychologists have been instrumental in altering treatment protocols to reduce the risk of neurocognitive damage (e.g., Rowland et al, 1984).…”

Section: Understanding and Reducing Neuropsychological Effectsmentioning

confidence: 99%

“…Certain cancers (e.g., brain tumors) and treatments (e.g., chemotherapies that cross the blood–brain barrier, cranial irradiation, surgical resection) have neurotoxic effects on the developing brain that may result in short- and long-term impairment of neurocognition and school performance (Campbell et al, 2007; Robinson et al, 2010). Impacts on IQ, verbal and nonverbal reasoning, memory, attention, processing speed, and executive functioning remain significant concerns (Hocking & Alderfer, 2012). Data from pediatric psychologists and neuropsychologists have been instrumental in altering treatment protocols to reduce the risk of neurocognitive damage (e.g., Rowland et al, 1984).…”

Section: Key Psychological Contributions To Pediatric Oncology Carementioning

confidence: 99%

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The integration of psychology in pediatric oncology research and practice: Collaboration to improve care and outcomes for children and families.

Kazak¹,

Noll²

2015

American Psychologist

114

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Childhood cancers are life-threatening diseases that are universally distressing and potentially traumatic for children and their families at diagnosis, during treatment, and beyond. Dramatic improvements in survival have occurred as a result of increasingly aggressive multimodal therapies delivered in the context of clinical research trials. Nonetheless, cancers remain a leading cause of death in children, and their treatments have short- and long-term impacts on health and well-being. For over 35 years, pediatric psychologists have partnered with pediatric oncology teams to make many contributions to our understanding of the impact of cancer and its treatment on children and families and have played prominent roles in providing an understanding of treatment-related late effects and in improving quality of life. After discussing the incidence of cancer in children, its causes, and the treatment approaches to it in pediatric oncology, we present seven key contributions of psychologists to collaborative and integrated care in pediatric cancer: managing procedural pain, nausea, and other symptoms; understanding and reducing neuropsychological effects; treating children in the context of their families and other systems (social ecology); applying a developmental perspective; identifying competence and vulnerability; integrating psychological knowledge into decision making and other clinical care issues; and facilitating the transition to palliative care and bereavement. We conclude with a discussion of the current status of integrating knowledge from psychological research into practice in pediatric cancer.

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Section: Understanding and Reducing Neuropsychological Effectsmentioning

confidence: 99%

Section: Key Psychological Contributions To Pediatric Oncology Carementioning

confidence: 99%

The integration of psychology in pediatric oncology research and practice: Collaboration to improve care and outcomes for children and families.

Kazak¹,

Noll²

2015

American Psychologist

114

View full text Add to dashboard Cite

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“…This group of parents may be particularly vulnerable to reduced HRQL due to the neurological, physical and neurodevelopmental sequelae seen in PBTS (Hocking & Alderfer, 2012). The only known study to examine this among PBTS found that caregivers of children with brain tumors had significantly lower HRQL compared to normative scores for healthy adults (Chien et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Health-related quality of life in parents of pediatric brain tumor survivors at the end of tumor-directed therapy

Quast

Turner

McCurdy

et al. 2016

Journal of Psychosocial Oncology

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“…Radiation therapy is an effective treatment modality for many CNS tumors; however, this treatment may produce significant physical and psychosocial stress for both the child and parent [3–6]. Radiation therapy is particularly stressful for children, who must maintain precise body positioning to ensure delivery of radiation to the tumor and avoid unintended exposure to the developing brain [7].…”

Section: Introductionmentioning

confidence: 99%

Play-based procedural preparation and support intervention for cranial radiation

Grissom

Boles

Bailey

et al. 2015

Support Care Cancer

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Purpose The primary objective of this study was to examine the relationship between play-based procedural preparation and support intervention and use of sedation in children with central nervous system (CNS) tumors during radiation therapy. The secondary objective was to analyze the cost-effectiveness of the intervention compared to costs associated with daily sedation. Methods A retrospective chart review was conducted, and 116 children aged 5–12 years met criteria for inclusion. Outcome measures included the total number of radiation treatments received, the number of treatments received with and without sedation, and the type and duration of interventions, which consisted of developmentally appropriate play, education, preparation, and distraction provided by a certified child life specialist. Results The results of univariate analyses showed that age, tumor location, and total number and duration of interventions were significantly associated with sedation use during radiation therapy. Multivariate analyses showed that, after adjustment for age, tumor location, and craniospinal radiation, a significant relationship was found between the total number and duration of the interventions and sedation use. The implementation of a play-based procedural preparation and support intervention provided by a certified child life specialist significantly reduced health-care costs by decreasing the necessity of daily sedation. Conclusions Support interventions provided by child life specialists significantly decreased both sedation use and the cost associated with daily sedation during cranial radiation therapy in children with CNS tumors. This study supports the value of the child life professional as a play-based developmental specialist and a crucial component of cost-effective healthcare.

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Neuropsychological Sequelae of Childhood Cancer

Cited by 8 publications

References 81 publications

The integration of psychology in pediatric oncology research and practice: Collaboration to improve care and outcomes for children and families.

The integration of psychology in pediatric oncology research and practice: Collaboration to improve care and outcomes for children and families.

Health-related quality of life in parents of pediatric brain tumor survivors at the end of tumor-directed therapy

Play-based procedural preparation and support intervention for cranial radiation

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