Neuropsychological, Behavioral, and Quality of Life Outcomes in Children and Adolescents with Sickle Cell Disease Treated with Nonmyeloablative Matched Sibling Donor Hematopoietic Cell Transplantation: A case series.
Abstract:Background/Objectives. Despite advances in the treatment of sickle cell
disease (SCD), cerebrovascular and cognitive consequences can be
lifelong. Hematopoietic cell transplantation (HCT) is an established
curative therapy and recent studies have demonstrated efficacy with
reduced toxicity nonmyeloblative (NMA) regimens, but little is known
about neuropsychological outcomes. The objective of this study was to
describe neuropsychological, behavioral, and quality of life outcomes
with medical correlates in child… Show more
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