Abstract:Stroke is a leading threat to human life. Metabolic dysfunction of glucose may play a key role in stroke pathophysiology. Pharmacological hypothermia (PH) is a potential neuroprotective strategy for stroke in which the temperature can be decreased safely. The present study determined whether neuroprotective PH with chlorpromazine and promethazine (C+P) plus dihydrocapsaicin (DHC) improved glucose metabolism in acute ischemic stroke. A total of 208 adult male Sprague-Dawley rats were randomly divided into the f… Show more
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