Neuroprotective effects of flavonoids: endoplasmic reticulum as the target
Bita Amiri,
Maryam Yazdani Tabrizi,
Mahdyieh Naziri
et al.
Abstract:The incidence of neurological disorders, particularly age-related neurodegenerative pathologies, exhibits an alarming upward trend, while current pharmacological interventions seldom achieve curative outcomes. Despite their diverse clinical presentations, neurological diseases often share a common pathological thread: the aberrant accumulation of misfolded proteins within the endoplasmic reticulum (ER). This phenomenon, known as ER stress, arises when the cell’s intrinsic quality control mechanisms fail to cop… Show more
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