“…To date, a wide range of physical therapy modalities has been proposed and employed to treat motor impairment in PD (Ceravolo et al, 2001;Picelli et al, 2012a,b;Carda et al, 2012;Picelli et al, 2013Picelli et al, , 2015Smania et al, 2013;Tomlinson et al, 2013). In particular, the implementation of physical activity programs for people with PD has resulted in improvements in daily activities, motor performance, ambulation and overall functional independence (Lau et al, 2011). Furthermore, in experimental animal models of PD, aerobic exercise has been shown to improve neurochemical and mitochondrial function, with a positive impact on cognitive and emotional aspects of behavior (Pothakos et al, 2009;Pietrelli et al, 2012;Tuon et al, 2012Tuon et al, , 2014 Cognitive-motor relationships have been explored in patients with PD (Domellöf et al, 2011;Poletti et al, 2012).…”