Neuroprotective Effect of White Nelumbo nucifera Gaertn. Petal Tea in Rats Poisoned with Mancozeb

Intui, Ketsarin; Nuchniyom, Pimchanok; Laoung-on, Jiraporn; Jaikang, Churdsak; Quiggins, Ranida; Sudwan, Paiwan

doi:10.3390/foods12112175

Cited by 3 publications

(1 citation statement)

References 75 publications

(101 reference statements)

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“…KBD consists of three herbs: Nelumbo nucifera (petals), Piper nigrum (fruits), and Centella asiatica (aerial part). The petals of N. nucifera were found to contain many bioactive compounds with antioxidant, anti-inflammatory, neuroprotective, and anticancer activities [3,4]. In turn, the fruits of P. nigrum or black pepper, which display anti-inflammatory, antioxidant, anticancer, antidepressant, and analgesic activities [5,6], were found to contain the alkaloid piperine as a major constituent, in addition to polyphenols and flavonoids [7,8], while C. asiatica, which has antioxidant, antiulcer, antidepressant, and anti-inflammatory activities [9,10], contains asiaticoside, polyphenols, flavonoids, and carotenoids [11].…”

Section: Introductionmentioning

confidence: 99%

Approach of Supercritical Carbon Dioxide for the Extraction of Kleeb Bua Daeng Formula

Ngamkhae,

Monthakantirat,

Chulikhit

et al. 2023

Molecules

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Supercritical fluid extraction (SFE) is an innovative green technology for the extraction of phytochemicals from plants. Therefore, this study aimed to evaluate the application of SFE and to optimize the extraction conditions of the Thai herbal formula, Kleeb Bua Daeng (KBD). A Box–Behnken design (BBD) with response surface methodology (RMS) was used to determine the effect of the extraction time (30–90 min), temperature (30–60 °C), and pressure (200–300 bar) on response variables including the extraction yield, total phenolic content (TPC), total flavonoid content (TFC), total carotenoid content (TCC), and total anthocyanin content (TAC) of the KBD formula. The highest percentage extraction yield (3.81%) was achieved at 60 °C, 300 bar, and 60 min of the extraction time. The highest TPC (464.56 mg gallic acid equivalents/g extract), TFC (217.19 mg quercetin equivalents/g extract), and TCC (22.26 mg β-carotene equivalents/g extract) were all achieved at 60 °C, 250 bar, and 90 min of the extraction time. On the contrary, it was not possible to quantify the total anthocyanin content as anthocyanins were not extracted by this method. The results indicated that SFE-CO2 is a suitable method of extraction for a green recovery of phytochemicals with low and moderate polarity from the KBD formula.

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Section: Introductionmentioning

confidence: 99%

Approach of Supercritical Carbon Dioxide for the Extraction of Kleeb Bua Daeng Formula

Ngamkhae,

Monthakantirat,

Chulikhit

et al. 2023

Molecules

View full text Add to dashboard Cite

show abstract

Approach of Supercritical Carbon Dioxide for the Extraction of Kleeb Bua Daeng Formula

Ngamkhae,

Monthakantirat,

Chulikhit

et al. 2023

Preprint

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Supercritical fluid extraction (SFE) is an innovative green technology for the extraction of phytochemicals from plants. Therefore, this study aimed to evaluate the application of SFE and to optimize the extraction condition of the Thai herbal formula, Kleeb Bua Daeng (KBD). A Box-Behnken design (BBD) with response surface methodology was used to determine the effect of extraction time, temperature, and pressure on response variables including extraction yield, total phenolic content (TPC), total flavonoid content (TFC), total carotenoid content (TCC) and total anthocyanin content (TAC) of KBD formula. The highest percentage extraction yield, TPC, TFC, and TCC of the extracts were 3.81%, 464.56 mg gallic acid equivalents/g extract, 217.19 mg quercetin equivalents/g extract, and 22.26 mg β-carotene equivalents/g extract, respectively. The results indicated that SFE is a suitable method of extraction for green recovery of some phytochemicals from the KBD formula.

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Bioactives of the Freshwater Aquatic Plants, Nelumbo nucifera and Lemna minor, for Functional Foods, Cosmetics and Pharmaceutical Applications, with Antioxidant, Anti-Inflammatory and Antithrombotic Health Promoting Properties

Seferli,

Kotanidou,

Lefkaki

et al. 2024

Applied Sciences

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Despite significant progress, certain inflammation related to chronic disorders, including cardiovascular diseases (CVD) and cancer, still present high mortality rates. Thus, further study is needed to address such pathologies more appropriately. Apart from classic therapeutics, natural bioactives with less toxic side effects have gained attention, including those with potential pharmaceutical properties derived from several plants. Within this article, the potential utilization of freshwater aquatic plants as sources of bioactives with antithrombotic, anti-inflammatory and antioxidant properties is outlined. Emphasis is given to a well-established aquatic plant with known but not fully clarified and overviewed bio-functional and pharmaceutical properties, the Chinese lotus (Nelumbo nucifera), as well as to a so far neglected aquatic plant, Lemna minor, which has not yet been thoroughly reviewed for such applications. The latent usually grows naturally in large numbers at the surface of stored water basins of retrieved water from the last stages of wastewater treatment facilities. The continuous growth of this aquatic plant in such conditions further suggests that it can be a sustainable source of natural bioactives, if appropriately valorized, with an economic benefit and in a friendly environmental approach. The abundant content of both freshwater aquatic plants in bioactive components with potent antioxidant, anti-inflammatory and antithrombotic activities is thoroughly outlined, while their applications as functional ingredients in several functional products (functional foods, cosmetics and pharmaceuticals) are also discussed. The outlined outcomes urge further study of both aquatic plants and especially of Lemna spp. to fully elucidate their potential as alternative sustainable sources of bioactive ingredients for functional foods, supplements, nutraceuticals, nutricosmetics, cosmeceuticals, cosmetics and pharmaceutical products with health-promoting properties against inflammation and thrombosis related manifestations and their associated chronic disorders.

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Neuroprotective Effect of White Nelumbo nucifera Gaertn. Petal Tea in Rats Poisoned with Mancozeb

Cited by 3 publications

References 75 publications

Approach of Supercritical Carbon Dioxide for the Extraction of Kleeb Bua Daeng Formula

Approach of Supercritical Carbon Dioxide for the Extraction of Kleeb Bua Daeng Formula

Approach of Supercritical Carbon Dioxide for the Extraction of Kleeb Bua Daeng Formula

Bioactives of the Freshwater Aquatic Plants, Nelumbo nucifera and Lemna minor, for Functional Foods, Cosmetics and Pharmaceutical Applications, with Antioxidant, Anti-Inflammatory and Antithrombotic Health Promoting Properties

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