Neuroplasticity and Successful Cognitive Aging

Vance, David E.; Kaur, Jaspreet; Fazeli, Pariya L; Talley, Michele; Yuen, Hon K.; Kitchin, Beth; Lin, Feng

doi:10.1097/jnn.0b013e3182527571

Cited by 23 publications

(18 citation statements)

References 48 publications

(68 reference statements)

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“…Within the framework of cognitive reserve and neuroplasticity, computer-based cognitive training creates physiologic changes in the brain that increase cognitive reserve (Lampit, Hallock, Suo, Naismith, & Valenzuela, 2015). Cognitive reserve refers to the number and strength of neural connections in the brain (Vance, Kaur, et al, 2012). The more cognitive reserve that one has, the better the brain is able to function.…”

Section: Cognitive Reserve and Neuroplasticitymentioning

confidence: 99%

Computer-Based Cognitive Training for Chemotherapy-Related Cognitive Impairment in Breast Cancer Survivors

Bail

Meneses

2016

CJON

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This review suggests that computer-based cognitive training may enhance cognitive function in BCS with chemotherapy-related cognitive impairment. Oncology nurses are in a unique position to support BCS experiencing chemotherapy-related cognitive impairment. In addition to acknowledging BCS' concerns, screening for other potential factors, and providing education on healthy living, nurses may suggest computer-based cognitive training as an approach to managing chemotherapy-related cognitive impairment. Future research should use imaging and larger populations.

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Section: Cognitive Reserve and Neuroplasticitymentioning

confidence: 99%

Computer-Based Cognitive Training for Chemotherapy-Related Cognitive Impairment in Breast Cancer Survivors

Bail

Meneses

2016

CJON

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“…Cognitive reserve refers to the maximum amount of damage the brain can absorb and continue to allow for normal cognitive processing (Vance et al, 2012). It is likely that both disease and treatment-based factors (e.g., chemotherapy) may reduce cognitive reserve through oxidative stress, increased cortisol levels, neuroinflammation, or numerous other potential mechanisms resulting in the type of subtle but disturbing deficits described in prior studies (Meyers, 2013).…”

Section: Implications For Researchmentioning

confidence: 96%

Attention and Memory Deficits in Breast Cancer Survivors

Frank

Vance

Jukkala

et al. 2014

Journal of Neuroscience Nursing

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Breast cancer survivors (BCSs) commonly report deficits in attention and memory, cognitive functions crucial for daily optimal functioning. Perceived deficits are reported before, during, and after adjuvant therapy and affect quality of life throughout survivorship. Deficits of attention and memory are particularly disruptive for BCSs working or attending school who report that subtle impairment diminishes their confidence and their performance at all levels of occupation. Chemotherapy and endocrine therapy contribute to attention and memory deficits, but research findings have not fully established the extent or timing of that influence. Fortunately, potential interventions for attention and memory deficits in BCSs are promising. These include cognitive remediation therapies aimed at training for specific areas of deficit, cognitive behavioral therapies aimed at developing compensatory strategies for areas of deficit, complementary therapies, and pharmacologic therapies.

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“…Furthermore, older BCS are increasingly being offered more aggressive treatment (Balasubramanian et al, 2012). Cognitive reserve is a theoretical concept reflecting the maximum amount of brain injury a person can accommodate before showing impaired performance (Vance et al, 2012) and is known to decline with healthy aging (Vance, McNees, & Meneses, 2009). It has been suggested that cognitive deficits after chemotherapy in BCS are related to decreased cognitive reserve .…”

Section: Chemotherapy and Cognitive Deficits In Bcsmentioning

confidence: 99%

Cognitive Deficits in Breast Cancer Survivors After Chemotherapy and Hormonal Therapy

Frank

Vance

Triebel

et al. 2015

Journal of Neuroscience Nursing

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Adjuvant treatments, specifically chemotherapy and hormonal therapy, have dramatically increased breast cancer survival, resulting in increased attention to the residual effects of treatment. Breast cancer survivors (BCS) frequently report that cognitive deficits are a particular source of distress, interfering with many aspects of quality of life. The literature on neuropsychological performance measures in BCS supports the reality of subtle cognitive deficits after both chemotherapy and hormonal therapy. This premise is supported by recent imaging studies, which reveal anatomical changes after chemotherapy as well as changes in patterns of neural activation while performing cognitive tasks. This review suggests that, even when performance on neuropsychological performance measures is within normal limits, BCS may be using increased cognitive resources in the face of reduced cognitive reserve. Potential interventions for cognitive deficits after adjuvant therapy include prescriptions for healthy living, pharmacotherapy, complementary therapy, and cognitive remediation therapy directed toward specific cognitive deficits or a combination of several strategies.

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Neuroplasticity and Successful Cognitive Aging

Cited by 23 publications

References 48 publications

Computer-Based Cognitive Training for Chemotherapy-Related Cognitive Impairment in Breast Cancer Survivors

Computer-Based Cognitive Training for Chemotherapy-Related Cognitive Impairment in Breast Cancer Survivors

Attention and Memory Deficits in Breast Cancer Survivors

Cognitive Deficits in Breast Cancer Survivors After Chemotherapy and Hormonal Therapy

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