Neuropeptide QRFP decreased food intake in the lateral hypothalamus
Olga Zagoracz,
Tamas Ollmann,
Laszlo Peczely
et al.
Abstract:Severe eating disorders, such as obesity, bulimia, and anorexia keep increasing to epidemic proportions worldwide. Understanding of neuropeptides’ role in complex hunger/satiety mechanisms may allow new prospectives for treatment and prevention. Pyroglutamylated arginine-phenylalanine-amide peptides (QRFPs) are thought to enhance feeding following the central administration. In our study, QRFP-26 was delivered into the lateral hypothalamic area (LHA) of male Wistar rats by direct microinjections, as QRFP-26 ex… Show more
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