“…Late neurologic dysfunction after HCT may affect the central nervous system (CNS) and peripheral nervous system and are more frequent after allogeneic HCT ( Table 10 , Supplementary Table S14 ) [ 235 – 237 ]. Potential causes include infection or immunosuppression (with CNIs), neurotoxic chemotherapy (eg, methotrexate, cytarabine, busulfan, thiotepa) and other medications, TA-TMA, cranial radiation or TBI, radiation-induced vasculitis, underlying disease (eg, cerebrovascular disease, sickle cell disease, adenosine deaminase deficiency), CNS relapse of the original disease, PTLD, subsequent neoplasms (local effects or paraneoplastic syndromes) and, finally by exclusion, cGVHD [ 238 ].…”