Neuropathology of two fatal cases of measles in the 1988–1989 Houston epidemic

Chickenpox, Measles, and Mumps

“…Myelin basic protein has been shown in the cerebrospinal fluid of patients with measles encephalitis, and the pathologic process has been likened to experimental allergic encephalitis as produced in animal models [424]. One theory regarding pathogenesis is that measles virus has an epitope similar to the epitope of the encephalitogenic sequence in central nervous system myelin (i.e., an instance of molecular mimicry leading to disease) [425].…”

Subacute Measles Encephalitis with AIDS Diagnosed by Fine Needle Aspiration Biopsy

“…It is characterized by absence of the measles virus and by the presence of demyelination, necrosis, vascular damage and hemorrhage. 9,16 SSPE develops after a latent period of a few years, beginning clinically with cognitive and behavioral changes. It progresses slowly over a period of one to three years, and the patient later develops myoclonus, choreoathetosis, dystonia and rigidity.…”

Measles and Secondary Hemophagocytic Lymphohistiocytosis

“…We conducted a PubMed search and found 5 articles that described 6 cases of HLH in patients with measles ( 1 – 5 ). Pneumonia was described in all of them ( 1 – 5 ), and central nervous system involvement was described in 3 ( 1 , 4 ).…”

“…Pneumonia was described in all of them ( 1 – 5 ), and central nervous system involvement was described in 3 ( 1 , 4 ). Four cases occurred in children, 3 of them immunocompetent ( 1 , 3 – 5 ).…”

“…Pneumonia was described in all of them ( 1 – 5 ), and central nervous system involvement was described in 3 ( 1 , 4 ). Four cases occurred in children, 3 of them immunocompetent ( 1 , 3 – 5 ). The 2 adults were an immunocompetent 18-year-old man who had acute respiratory distress ( 2 ) and a 19-year-old man with acute lymphocytic leukemia who had measles pneumonia and acute hemorrhagic leukoencephalitis ( 1 ).…”