Neuropathologie der Listeriose

Intramedullary brain stem cyst and trapped IV ventricle after infection with Listeria monocytogenes

“…Besides inflammatory changes and meningeal fibrosis, cystic lesions within the III and IV ventricular subependymial layers were found, which were separated from the ventricular system only by a filmy membrane. These changes were most probably sequelae of the preceding ependymitis [4].…”

“…This last may be associated with encephalitis, in particular in the form of rhombencephalitis [1,2,4]. Typical clinical features include ventilatory or cardiac depression and occasionally neurological symptoms, such as seizures.…”

“…As listeriosis is often oligosymptomatic and findings are uncharacteristic, diagnosis depends on appropriate microbiological assessment, which can be made most easily from ear swab or meconium [1,4]. Adequate and early antibiotic therapy can lead to total clinical restitution without any morphologic sequelae.…”

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IntroductionListeria monocytogenes is a gram-positive, non-sporeforming, flagellated bacillus, which is ubiquitous throughout the world [4,16].There are several studies on the sporadic endemic or epidemic occurrence of listeriosis, in particular in rural regions [15]. The mode of transmission to humans is still not entirely known.

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