Neuropathic pain, antidepressant drugs, and inflammation: a narrative review
Giulia Catalisano,
Gioacchina Martina Campione,
Giulia Spurio
et al.
Abstract:Background
Neuropathic pain (NP) is a chronic and disabling condition, caused by a lesion or disease of the somatosensory nervous system, characterized by a systemic inflammatory state. Signs and associated symptoms are rarely recognized, and response to usual analgesic drugs is poor. Antidepressant drugs are first-line agents for the treatment of NP. This narrative review aims to summarize the role of antidepressant drugs in treating NP and their mechanism of action, focusing on the effects on… Show more
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