Neurons in the medial prefrontal cortex that are not modulated by hippocampal sharp-wave ripples are involved in spatial tuning and signaling upcoming choice
Hanna den Bakker,
Fabian Kloosterman
Abstract:The hippocampus is known to encode spatial information and reactivate experienced trajectories during sharp-wave ripple events. These events are thought to be key time-points at which information about learned trajectories is transferred to the neocortex for long-term storage. It is unclear, however, how this information may be transferred and integrated in downstream cortical regions. In this study, we performed high-density probe recordings across the full depth of the medial prefrontal cortex and in the hip… Show more
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