Neuronal regulation of bone and tendon injury repair: a focused review
Mingxin Xu,
Manyu Zhu,
Qizhi Qin
et al.
Abstract:Beyond the sensation of pain, peripheral nerves have been shown to play crucial roles in tissue regeneration and repair. As a highly innervated organ, bone can recover from injury without scar formation, making it an interesting model in which to study the role of nerves in tissue regeneration. As a comparison, tendon is a musculoskeletal tissue that is hypo-innervated, with repair often resulting in scar formation. Here, we reviewed the significance of innervation in three stages of injury repair (inflammator… Show more
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