Neuron Foundry Mach 8: A Concept of Multi-modal Neuro-supportive Energy Therapy Device for Treating Neurodegenerative Disorders

Abstract

The prevalence of neurodegenerative disorders is rising as the population ages, and many ailments, such as depression, Parkinson’s disease, Alzheimer’s disease, autism spectrum disorder, and multiple sclerosis, have intricate underlying mechanisms that are still poorly understood. The Neuron Foundry Mach 8 is a multi-modal neuro-supportive energy therapy device designed to treat neurodegenerative disorders through daily sessions. This device proposes to deliver safe and controlled energy therapy through multiple therapeutic pathways, including stimulating brain mitochondrial energy, supporting homeostasis within the brain’s immune system, increasing melatonin production within neuronal mitochondria, and triggering cellular communication through the brain’s white matter. By combining these unique energy-based treatments, this device holds promising potential for slowing, stopping, reversing, or at least reducing the effects of neurodegenerative diseases.

Postoperatively Noninvasive Optogenetic Stimulation via Upconversion Nanoparticles Enhancing Sciatic Nerve Repair

“…Traditional microsurgical approaches fail to address the complex cellular and molecular events involved in nerve repair, , and the intrinsic factors are insufficient to support successful nerve regeneration. − A prospective strategy is the utilization of artificial nerve scaffolds, allowing for the introduction of various exogenous signals and stimuli to promote nerve regeneration, such as neurotrophic factors, stem cells, chirality, gene transfection, and electrical stimulation. − Among these, electrical stimulation using electroactive materials enables the regulation of numerous cellular processes particularly in neural cells, including proliferation, migration, and neural conduction by modifying the charge transport of cell membrane potential through voltage-gated ion channels . However, the required device implantation for electricity delivery and indiscriminate current stimulation contribute to severe secondary damage at the nerve stumps.…”