Neurology and neurosciences

Vethanayagam, Natalie; Orme, Susie; Orrell, Alison; McKee, Kathleen; Dahlberg, Lena; Marsh, H O; Harland, Juliet; Smith, Graeme C.; Gilhooly, Mary; Parker, Stuart G.; McGarrigle, Christine; Hayakawa, Takahiro; Lawlor, Brian A.; Kenny, RoseAnne; Frewen, John; Finucane, Ciarán; Boyle, G.; Coen, RF

doi:10.1093/ageing/aft022

Cited by 2 publications

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“…Fundamental roles of carotenoids have been elucidated also in human metabolism. Indeed, their benefits for human health are mainly due to their antioxidant properties, and studies have correlated the consumption of several carotenoids with a reduced risk of cardiovascular diseases, low-density lipoprotein peroxidation and prostate cancer (Eggersdorfer & Wyss, 2018), with a key role also in bone homeostasis (Yamaguchi & Uchiyama, 2003) and eye health (Feeney et al, 2013) as precursors of vitamin A and retinoids (Kopsell & Kopsell, 2006).…”

Section: Introductionmentioning

confidence: 99%

The outer influences the inner: Postharvest UV-B irradiation modulates peach flesh metabolome although shielded by the skin

et al. 2021

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Section: Introductionmentioning

confidence: 99%

The outer influences the inner: Postharvest UV-B irradiation modulates peach flesh metabolome although shielded by the skin

et al. 2021

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Vision impairment and cognitive decline among older adults: a systematic review

et al. 2022

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ObjectivesThere has been increasing epidemiological research examining the association between vision impairment (VI) and cognitive impairment and how poor vision may be a modifiable risk factor for cognitive decline. The objective of this systematic review is to synthesise the published literature on the association of VI with cognitive decline, cognitive impairment or dementia, to aid the development of interventions and guide public policies pertaining to the relationship between vision and cognition.MethodsA literature search was performed with Embase, Medline and Cochrane library databases from inception to March 2020, and included abstracts and articles published in peer-reviewed journals in English. Our inclusion criteria included publications that contained subjective/objective measures of vision and cognition, or a diagnosis of VI, cognitive impairment or dementia. Longitudinal or cross-sectional studies with ≥100 participants aged >50 years were included. The search identified 11 805 articles whose abstracts underwent screening by three teams of study authors. Data abstraction and quality assessment using the Effective Public Health Practice Project Quality Assessment Tool were performed by one author (NN). 10% of the articles underwent abstraction and appraisal by a second author (LA/VV), results were compared between both and were in agreement.Results110 full-text articles were selected for data extraction, of which 53 were cross-sectional, 43 longitudinal and 14 were case–control studies. The mean age of participants was 73.0 years (range 50–93.1). Ninety-one (83%) of these studies reported that VI was associated with cognitive impairment.ConclusionOur systematic review indicates that a majority of studies examining the vision–cognition relationship report that VI is associated with more cognitive decline, cognitive impairment or dementia among older adults. This synthesis supports the need for additional research to understand the mechanisms underlying the association between VI and cognitive impairment and to test interventions that mitigate the cognitive consequences of VI.

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Neurology and neurosciences

Cited by 2 publications

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The outer influences the inner: Postharvest UV-B irradiation modulates peach flesh metabolome although shielded by the skin

The outer influences the inner: Postharvest UV-B irradiation modulates peach flesh metabolome although shielded by the skin

Vision impairment and cognitive decline among older adults: a systematic review

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