Neurological soft signs in obsessive compulsive disorder with good and poor insight

Karadag, Filiz; Tümkaya, Selim; Kırtaş, Duygu; Efe, Muharrem; Alacam, Huseyin; Oğuzhanoğlu, Nalan Kalkan

doi:10.1016/j.pnpbp.2011.03.003

Cited by 34 publications

(36 citation statements)

References 37 publications

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“…We analyzed the effect of treatment condition (in terms of pre-post differences and responder and remission status) in the group of patients with the worst insight at baseline (n = 23), as reflected by a baseline OVIS score >6 (an OVIS score >6 was labeled 'high overvalued ideation' in earlier research [11,33] ). The subgroup analysis was based on a formal test of interaction, in an extended mixed-effects model and in an extended logistic regression analysis in which the original models were fully interacted with the 'worst insight at baseline' indicator.…”

Section: Discussionmentioning

confidence: 99%

“…To examine this, we used a t test to compare the mean OVIS score of our sample to that found in earlier studies presenting baseline OVIS means and SDs of referred patients with OCD. We found 6 studies [6,11,33,[36][37][38] in which a total of 319 patients participated. We meta-analyzed the OVIS scores of these 6 studies using the Cochrane method for combining groups (http://handbook.cochrane.org) and found that the mean OVIS score found in our sample was significantly higher.…”

Section: Discussionmentioning

confidence: 99%

“…This experimental cutoff was used in 2 earlier studies [11,33] to distinguish patients with high overvalued ideas. We found that the IBA was significantly more effective than CBT in the subgroup of patients with really poor rather than limited insight.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Inference-Based Approach versus Cognitive Behavioral Therapy in the Treatment of Obsessive-Compulsive Disorder with Poor Insight: A 24-Session Randomized Controlled Trial

Visser

Megen

Oppen

et al. 2015

Psychother Psychosom

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Objective: Obsessive-compulsive disorder (OCD) with poor insight has severe consequences for patients; nonetheless, no randomized controlled trial has ever been performed to evaluate the effectiveness of any treatment specifically for poor-insight OCD. A new psychotherapy for OCD, the inference-based approach (IBA), targets insight in OCD by strengthening normal sensory-driven reality testing. The goal of the present study is to compare the effectiveness of this new treatment to the effectiveness of cognitive behavior therapy (CBT) for patients with OCD with poor insight. Method: A randomized controlled trial was conducted, in which 90 patients with OCD with poor insight received either 24 CBT sessions or 24 IBA sessions. The primary outcome measure was the Yale-Brown Obsessive Compulsive Scale (YBOCS). Secondary outcome measures were level of insight, anxiety and depressive symptoms, and quality of life. Mixed-effects models were used to determine the treatment effect. Results: In both conditions, a significant OCD symptom reduction was reached, but no condition effects were established. Post hoc, in a small subgroup of patients with the worst insight (n = 23), it was found that the patients treated with the IBA reached a significantly higher OCD symptom reduction than the patients treated with CBT [estimated marginal mean = -7.77, t(219.45) = -2.4, p = 0.017]. Conclusion: Patients with OCD with poor insight improve significantly after psychological treatment. The results of this study suggest that both CBT and the IBA are effective treatments for OCD with poor insight. The IBA might be more promising than CBT for patients with more extreme poor insight.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Inference-Based Approach versus Cognitive Behavioral Therapy in the Treatment of Obsessive-Compulsive Disorder with Poor Insight: A 24-Session Randomized Controlled Trial

Visser

Megen

Oppen

et al. 2015

Psychother Psychosom

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“…[30] Karadağ ve arkadaşları 38 içgörüsü iyi OKB hastası, 26 içgörüsü az OKB hastası ve 32 sağlıklı kontrolün nörolojik yumuşak işaretlerinin oranını karşılaştırmışlardır. [31] Nörolojik yumuşak işaretler nörogelişimsel bir bozukluğa ikincil olarak ortaya çıkan, lokalize etmeyen minör nörolojik bulgulardır. Yumuşak işaretlerin değerlendirmesinde Nörolojik Değerlendirme Ölçeği kullanılmıştır.…”

Section: Okb'de İçgörü Azlığının Nörobiyolojik-nöropsikolojik Temelleriunclassified

“…Bu grubun biyolojik özelliklerinin klasik OKB hastalarından farklı olduğu akla gelmektedir. [31] İçgörüsü az OKB hastalarının özgül bir nöropsikolojik profil sergilediğinin ortaya konması bu grubun biyolojik özelliklerinin incelenmesinin ve tedavi stratejilerinin geliş-tirilmesinin önünü açacağından önemlidir. Yüz elli OKB hastasının 177 sağlıklı kontrolle karşılaştırıldığı çalışmada içgörünün değerlendirilmesinde BABS kullanılmış-tır.…”

Section: Okb'de İçgörü Azlığının Nörobiyolojik-nöropsikolojik Temelleriunclassified

Obsessive Compulsive Disorder with Poor Insight

Bulut¹,

Fıstikçı²,

Topçuoğlu³

2014

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychia

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ÖzetObsesif kompulsif bozukluk ileri derecede yeti yitimine neden olabilen ruhsal bir bozukluktur. OKB hastalarında içgörü hastalığın ilk tanımlanmasından bu yana tartışma konusudur. Önceleri, nörotik bozukluklardan biri olarak kabul edilen obsesif kompulsif bozuklukta hastaların belirtilerini tamamen saçma ve abartılı bulmaları gerektiği düşünülmüştür. Ancak, obsesyonların ve kompulsiyonların her zaman egodistonik bulunacağı fikri giderek değişmiştir. İlk olarak Ruhsal Bozuklukların Tanısal ve Sayımsal El Kitabının 4. Baskısında (DSM-IV)'te obsesif kompulsif bozuklukta "içgörüsü az olan" ifadesine yer verilmiştir. İçgörüsü az olan ya da olmayan obsesif kompulsif bozukluğun içgörünün korunduğu obsesif kompulsif bozukluktan sosyodemografik, klinik ve tedavi özellikleri bakımından farklılıkları olabilir. Obsesif kompulsif bozuklukta belirti tiplerine göre içgörü düzeyleri değişebilmektedir. İçgörüsü az obsesif kompulsif bozukluk, obsesif kompulsif bozukluğun şiddetli bir formu ya da farklı özellikler gösteren bir alt tip olabilir. DSM-5 ile birlikte içgörü belirteci sınıflan-dırmadan çıkarılmıştır. Obsesif kompulsif bozukluk hastalarının içgörülerinin bir yelpaze ya da süreklilik şeklinde ele alınması gerekir.Anahtar sözcükler: Obsesif kompulsif bozukluk, içgörü, sınıflandırma. AbstractObsessive-compulsive disorder

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Insight in Obsessive‐Compulsive Disorder

Wu¹,

Lewin²

2017

The Wiley Handbook of Obsessive Compulsive Disorders

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Neurological soft signs in obsessive compulsive disorder with good and poor insight

Cited by 34 publications

References 37 publications

Inference-Based Approach versus Cognitive Behavioral Therapy in the Treatment of Obsessive-Compulsive Disorder with Poor Insight: A 24-Session Randomized Controlled Trial

Inference-Based Approach versus Cognitive Behavioral Therapy in the Treatment of Obsessive-Compulsive Disorder with Poor Insight: A 24-Session Randomized Controlled Trial

Obsessive Compulsive Disorder with Poor Insight

Insight in Obsessive‐Compulsive Disorder

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