Neurological sequelae of COVID-19: a review

Peterson, Christopher; Sarangi, Ashish; Bangash, Fariha

doi:10.1186/s41983-021-00379-0

Cited by 33 publications

(31 citation statements)

References 114 publications

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“…Symptoms of mental illnesses such as depression, anxiety, obsessive-compulsive, suicidal, neurological, cognitive, and other disorders have increased overall during the COVID-19 pandemic, as clinical, financial, and psychological stress continues. [30][31][32] Our study described the depression, anxiety, and fears observed in HCWs during the waves of COVID-19.…”

Section: Discussionmentioning

confidence: 95%

Factors Affecting the Psychological Well-Being of Health Care Workers During the COVID-19 Crisis

Alharthi¹,

Alshomrani²,

Bazaid³

et al. 2022

PRBM

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Background Health care workers (HCWs) are a group that especially suffered during the COVID-19 pandemic. In addition to facing the stress of dealing with patients and social isolation, they had to worry about being infected themselves and transmitting the infection to their families. This study evaluated the fear, anxiety, and depression experienced by HCWs during the COVID-19 crisis. Subjects and Methods The sample size was 541 HCWs. Data collection was done using an online validated questionnaire through Google Docs, sent to HCWs by email and WhatsApp groups. We assessed depression and anxiety with the 4-item Patient Health Questionnaire-4 (PHQ-4), while evaluating fear with the Fear of COVID-19 Scale (FCV-19S). Results A statistically significant difference was found in the perception of fear between married and unmarried people, and between those with colleagues who had died from COVID-19 infection and those without. There was a significant relation between HCWs’ anxiety and a history of death from COVID-19 infection, either of friends or of close relatives. The prevalence of depression was 18.48% in the tested sample of HCWs. Participants who had close relatives or friends infected with COVID-19 showed a significantly higher degree of depression. The age group <30 and those working 20 to 30 hours weekly showed higher degrees of anxiety and depression. Conclusion Sociodemographic variables such as age, marital status, and working area had a significant impact on the mental and psychological health of HCWs during the COVID-19 crisis. HCWs who lost patients due to COVID-19 had a significantly higher prevalence of fear, depression, and anxiety.

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Section: Discussionmentioning

confidence: 95%

Factors Affecting the Psychological Well-Being of Health Care Workers During the COVID-19 Crisis

Alharthi¹,

Alshomrani²,

Bazaid³

et al. 2022

PRBM

View full text Add to dashboard Cite

show abstract

“…Neurological and psychiatric sequelae of COVID-19 are actively being studied. A recent review summarized COVID-19 neurological sequela, ranging from olfactory and gustatory dysfunction and other cranial nerve impairments, headaches, cognitive, memory, and sleep changes, fatigue, akinetic mutism, stroke, worsening of dementia, and Gillian-Barre syndrome [ 62 ]. Anxiety, depression, posttraumatic stress disorder (PTSD), somatization, OCD, and suicide were associated with psychiatric effects during the pandemic [ 63 ].…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Difficulties and Treatment Challenges of a Young Patient With Severe Acute Psychosis and Complete Recovery

Siembida¹,

Mohammed²,

Chishty³

et al. 2022

Cureus

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First break psychosis in young adults is sometimes presented as a dichotomous model of organic or substance-induced etiology or a primary psychiatric disorder on the schizophrenia spectrum and related disorders. In this case of a young adult with a typical age of onset for psychotic symptoms also presenting with cannabis use, excessive vaping, history of COVID-19 illness, pineal cyst, and extreme elevation of blood pressure, the diagnostic certainty decreases. Increased risk of progression to schizophrenia in individuals with cannabis use disorder and genetic loading has been extensively reported in the literature. Clinicians may face significant diagnostic and treatment challenges when managing a patient with severe psychotic symptoms. For the clinicians acutely managing such patients facing these exact questions of unknown certainty in progression to full-blown schizophrenia, we highlight a case of severe acute psychosis and complete recovery on a first-generation antipsychotic and mood stabilizer.

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“…Beyond the significant respiratory complaints of COVID-19, there has been an increasing number of reported neurological complications of the disease. [37][38][39][40] A nationwide retrospective observational study in Italy showed 72.1% of the 646 patients surveyed reported neurological symptoms during their COVID-19 infection.…”

Section: Covid-19 and Its Neurological Manifestationsmentioning

confidence: 99%

Effects of COVID-19 on Multiple Sclerosis Relapse: A Comprehensive Review

Topolski

Soti

2022

Int J Med Stud

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Multiple Sclerosis is a chronic inflammatory disease. It is characterized by demyelinating lesions throughout the central nervous system. Patients suffering from multiple sclerosis constitute a vulnerable population to coronavirus disease-2019. This review focuses on the effects of coronavirus disease-2019 on relapse and symptom exacerbation in multiple sclerosis patients and their treatment. It highlights how the blood-brain barrier may be compromised by severe acute respiratory syndrome coronavirus 2, allowing inflammatory mediators and lymphocytes to infiltrate the central nervous system. This may increase the risk of relapse in multiple sclerosis patients. Also, in patients who did not have a prior history of multiple sclerosis, coronavirus disease-2019 has been found to impact multiple sclerosis onset and pathogenesis. However, more comprehensive research is required to fully understand the interplay between multiple sclerosis and coronavirus disease-2019.

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Neurological sequelae of COVID-19: a review

Cited by 33 publications

References 114 publications

Factors Affecting the Psychological Well-Being of Health Care Workers During the COVID-19 Crisis

Factors Affecting the Psychological Well-Being of Health Care Workers During the COVID-19 Crisis

Diagnostic Difficulties and Treatment Challenges of a Young Patient With Severe Acute Psychosis and Complete Recovery

Effects of COVID-19 on Multiple Sclerosis Relapse: A Comprehensive Review

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