Neurological recovery after prolonged coma from carbon monoxide poisoning

Zink, Robert S.; Adkinson, Cheryl; Davies, Scott F.

doi:10.1016/0735-6757(94)90283-6

Cited by 1 publication

(4 citation statements)

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“…Some examples of late recovery have been reported in the literature. Zink et al 4 reported two patients (19 and 30 years of age) who regained consciousness 17 and 35 days after coma and were able to live on their own after 1 year. The two patients in this report were as young as the patient in our study (23 years of age) who recovered well.…”

Section: Discussionmentioning

confidence: 99%

“…Only a small percentage of CO-poisoned patients have a clinical course that is characterized by stability after initial treatment followed by prolonged coma. 4 For patients in a prolonged coma, the prognosis is generally poor; however there have been several reports of late recoveries from prolonged postcardiac arrest coma. [5][6][7][8][9][10] For patients with severe CO poisoning in a prolonged coma, there are also some reports of late recovery.…”

Section: Introductionmentioning

confidence: 99%

“…Strohl et al 11 reported a patient who regained consciousness after 35 days in 1 Department of Hyperbaric Oxygen Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China 2 a prolonged coma after CO poisoning. Zink et al 4 reported two patients who regained consciousness 17 and 35 days after coma, and were able to live independently after 1 year; however, the likelihood of late recovery is unknown.…”

Section: Introductionmentioning

confidence: 99%

“…Only a small percentage of CO-poisoned patients have a clinical course that is characterized by stability after initial treatment followed by prolonged coma. 4…”

Section: Introductionmentioning

confidence: 99%

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Prognosis of patients in prolonged coma after severe carbon monoxide poisoning

Gao

Yang

et al. 2021

Hum Exp Toxicol

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Background: Late recovery in patients following prolonged coma from carbon monoxide poisoning have been reported, but the probability is unclear. The purpose of this research was to assess the prognosis of patients in prolonged coma after severe carbon monoxide poisoning and related clinical and imaging features. Methods: There were 13 patients who had been in a state of coma for >7 days after acute carbon monoxide poisoning in the retrospective observational study, and demographic data, clinical data, laboratory data, complications, and image data were collected. Outcome was assessed by means of the Glasgow outcome scale after 1 year. The relationship between complications and imaging manifestations and prognosis was also analyzed. Results: One year after severe carbon monoxide poisoning, two patients (15.4%) had died (GOS 1), nine (69.2%) were in a persistent vegetative state (GOS 2), one (7.7%) was moderately disabled (GOS 4), and one (7.7%) achieved a good recovery (GOS 5) with minimal disability. Conclusions: Most patients with prolonged coma after severe carbon monoxide poisoning had a poor prognosis, although the younger patients had a better prognosis. Respiratory failure, hypotension and renal failure during the course of the disease were associated with a poor prognosis. The prognosis of patients with injuries in two sites in early CT was poor. Multiple lesions (≥3) and extensive white matter damage (Fazekas grade (PVH or DWMH) = 3) on MRI of chronic phase were also associated with a poor prognosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Only a small percentage of CO-poisoned patients have a clinical course that is characterized by stability after initial treatment followed by prolonged coma. 4…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations