Neurological problems in the newborn

Rennie, Janet M.; Huertas-Ceballos, Ángela; Boylan, Geraldine B.; Shah, Divyen K.; Robertson, Nicola J.; Groenendaal, Floris; Dyet, Leigh; Barth, Peter; Robb, Stephanie; Muntoni, Francesco; Hagmann, Cornelia

doi:10.1016/b978-0-7020-3479-4.00041-6

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“…Clonic seizures typically present with rhythmic jerking at 1–4 Hz that is not dampened by putting the examiner's hand against the limb. Clonic seizures may start on one side of the face or in one limb and spread 3. They may be focal or multifocal.…”

Section: Clinical Seizures In the Newbornmentioning

confidence: 99%

“…However, several other conditions may predispose a newborn to seizures, such as neonatal abstinence syndrome, hypoglycaemia and inborn errors of metabolism (see table 1). 3 Of 92 newborns with electrographic seizures recorded over a 4-year period at a single centre by Scher et al, 4 60% had seizures in the first 48 h of life. Two-thirds of the infants were preterm and 45% (28/62) of these had experienced severe intraventricular haemorrhage (ie, with accompanying ventricular dilatation or intraparenchymal extension).…”

Section: Introductionmentioning

confidence: 99%

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Monitoring of seizures in the newborn

Shah¹,

Boylan

Rennie

2010

Arch Dis Child Fetal Neonatal Ed

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Neonatal seizures are a distinct and not uncommon sign of neurological disease in the newborn, most often occurring in association with hypoxic-ischaemic encephalopathy at term. The diagnosis and monitoring of seizures in the newborn is a considerable challenge, with many suspected clinical seizures having no electrographic correlates, while many electrographic seizures have no clinical correlate. Continuous video-EEG is the gold standard for seizure monitoring, but few centres have the resources or expertise required. Amplitude-integrated EEG can be a helpful monitoring tool in experienced hands, but has potential for error when used by inexperienced staff. Automated seizure detection algorithms show much promise and some cotside systems are already available. The efficiency and accuracy of these systems is likely to improve.

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Section: Clinical Seizures In the Newbornmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%