2021
DOI: 10.5005/jp-journals-10071-23723
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Neurological Manifestations of COVID-19: A Series of Seven Cases

Abstract: H ighlights There is no dearth of literature on pulmonary involvement in COVID-19 infection. However, extra-pulmonary manifestations are rare and can be easily missed during this pandemic. Our case series hopes to highlight the fact that neurological manifestations of COVID-19 infection are likely to be overlooked. Hence, a low threshold of clinical suspicion and testing for COVID-19 infection is needed in cases presenting with primary neurological symptoms. This will facilitate quicke… Show more

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Cited by 11 publications
(3 citation statements)
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“…Filosto et al [14] published a series of 34 GBS cases in the North Italian population of 8.4 million, and calculated a rate of 47.9 cases of GBS per 100 000 COVID-19 infections. In a prior case series published by our hospital (Goel et al [15]), we have also reported neurological manifestations of COVID-19 disease presenting to our hospital, out of which 2 presented with GBS.…”
Section: Discussionsupporting
confidence: 51%
“…Filosto et al [14] published a series of 34 GBS cases in the North Italian population of 8.4 million, and calculated a rate of 47.9 cases of GBS per 100 000 COVID-19 infections. In a prior case series published by our hospital (Goel et al [15]), we have also reported neurological manifestations of COVID-19 disease presenting to our hospital, out of which 2 presented with GBS.…”
Section: Discussionsupporting
confidence: 51%
“…On the opposite side, Goel et al [ 11 ] proved that the most commonly reported COVID neurological complications are cerebrovascular accidents, encephalopathy, encephalitis, meningitis, and Guillain-Barr e syndrome (GBS).…”
Section: Discussionmentioning
confidence: 99%
“…8 Several studies have suspected that SARS-CoV2 may spread directly through systemic circulation to the cerebral or penetrate through the cribriform lamina of the ethmoid bone through inflammatory response, immune mechanism, and microvascular disease. 7, 11 Angiotensin-converting enzymes II (ACE II) receptors found in the endothelial cell of the oral, nasal mucosa, and the nervous system may act as the entry point of the virus and cause neurological involvement in the patient. 12 Neurological symptoms can be a direct effect of virus neurotropism or a systemic consequence of immune-mediated mechanism after infection.…”
Section: Case Presentationmentioning
confidence: 99%