Neurological disease in pregnant females with COVID ‐19 may not only be attributable to SARS‐CoV ‐2

Abstract

To the EditorWe read with interest the review article by Magalhoes et al. about 18 SARS-CoV-2-infected pregnant females who developed neurological complications and were published until the November 25, 2021. 1Central nervous system (CNS) complications from the SARS-CoV-2 infection diagnosed in these cohort included delirium (n = 1), posterior reversible encephalopathy syndrome (PRES) (n = 4), ischemic

Reply: Neurological disease in pregnant females with COVID ‐19 may not only be attributable to SARS‐CoV ‐2

“…The peer review history for this article is available at https://publo ns.com/publo n/10.1111/ane.13663. João Eudes Magalhães 1,2 Pedro Augusto Sampaio-Rocha-Filho…”

“…We appreciate the interest and observations of Professor Finsterer 1 regarding our recently published review article. 2 The other three pregnant women with COVID‐19 and neurological complications, 3 , 4 , 5 which he identified, were not included in our original article, even though we had been careful during the search process using broad terms in several combinations as described in the Methods section.…”

“… 2 The other three pregnant women with COVID‐19 and neurological complications, 3 , 4 , 5 which he identified, were not included in our original article, even though we had been careful during the search process using broad terms in several combinations as described in the Methods section. 2 He summarized 1 a new stroke case 5 and two new cases of Guillain‐Barré syndrome (GBS) 3 , 4 in pregnant women with COVID‐19. Therefore, we have herein revised 10 patients with central nervous system (CNS) involvement (48%) and 11 patients with peripheral nervous system (PNS) involvement (52%) in order to compare with our previous results.…”

“…We agree that neurological conditions in pregnant women with COVID‐19 may not only be attributable to the SARS‐CoV‐2 infection. 1 The COVID‐19 pandemic limited further investigations and possibly led to the misidentification of neurologic complications in infected patients. Therefore, it was challenging to study the causal relationship, especially in pregnant women.…”