Neurological complications of connective tissue and other “collagen-vascular” diseases

A longitudinal study of autoantibodies against central nervous system tissue and gangliosides in connective tissue diseases

“…In SLE, the frequency of CNS complications 24 20 a Neuropsychiatric manifestation was de®ned as the presence of at least one``major'' symptom b Major neuropsychiatric symptoms consisted of cranial neuropathy (n = 8), mood disorder (n = 7), acute confusional state (n = 5), stroke (n = 4), anxiety disorder (n = 2), psychosis (n = 2), seizure (n = 2), chorea (n = 1), aseptic meningitis (n = 1) c Major neuropsychiatric symptoms consisted of mood disorder (n = 17), anxiety disorder (n = 3), cranial neuropathy (n = 1), acute confusional state (n = 1), psychosis (n = 1) d Major neuropsychiatric symptoms consisted of mood disorder (n = 2) varied between 18 and 61% of cases [1,3,4]. In our study 46% of patients with connective tissue disease showed features of major cerebral involvement.…”

“…In SLE, central nervous system (CNS) complications have been described in 18±61% of cases [1,3,4]. Neuropsychiatric manifestation in connective tissue diseases comprise psychotic conditions, mood disorders, acute confusional states, migraine, seizure, and stroke [1,3,5].…”

“…In SLE, central nervous system (CNS) complications have been described in 18±61% of cases [1,3,4]. Neuropsychiatric manifestation in connective tissue diseases comprise psychotic conditions, mood disorders, acute confusional states, migraine, seizure, and stroke [1,3,5]. The diagnosis of cerebral involvement can be dicult and has to be dierentiated from neurological complications which may be, for instance, due to uremia, hypertension, drug toxicity, or an association with neurological or psychiatric disorders.…”

Audio-vestibular disturbances in Behcet’s patients: report of 62 cases

“…Only 5% of patients present with neurological complaints, but 25-30% eventually develop neurological manifestations (Chajek and Fainaru, 1975;OÕDuffy and Goldstein, 1976). These neurological manifestations include brain stem lesions, organic confusional states, hemiparesis, and aphasia (Cohen and Hurd, 1981). Auditory and vestibular lesions, among the clinical manifestations of CNS involvement, were first described by Alajouanine et al (1961).…”

Co-Incidence of Guillain-Barré Syndrome and Spinal Cord Compression in Non-Hodgkin Lymphoma

“…Evidence indicates that cell-mediated cytotoxicity against myelin plays a central role in the pathogenesis (7,10). GBS occurring in a setting of extraneurallymphoma as weIl as other conditions marked by partial immunosuppression have been reported previously (4,5,8,10,14,15). Although the precise reason for the GBS to develop in our case can not be definitely stated, the presence of partial immunosuppression of the patient besides the antecedent flue-like syndrome and the surgery could possibly be triggering factors.…”