2012
DOI: 10.1016/b978-0-444-53502-3.00020-3
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Neurological complications in plasma cell dyscrasias

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Cited by 8 publications
(3 citation statements)
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References 160 publications
(165 reference statements)
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“…Peripheral neuropathy is common and is frequently associated with plasma cell dyscrasias, which may correspond to 10% of patients with idiopathic peripheral neuropathy and as high as 20% in patients with multiple myeloma. In this study, a high neurological compromise was found, with paresis of the lower limbs more frequent 24,25 . Bone lesions visualized on a conventional radiograph, which may include osteolytic lesions or the presence of fractures, are described in 80% of patients at the time of diagnosis.…”
Section: Methodssupporting
confidence: 48%
“…Peripheral neuropathy is common and is frequently associated with plasma cell dyscrasias, which may correspond to 10% of patients with idiopathic peripheral neuropathy and as high as 20% in patients with multiple myeloma. In this study, a high neurological compromise was found, with paresis of the lower limbs more frequent 24,25 . Bone lesions visualized on a conventional radiograph, which may include osteolytic lesions or the presence of fractures, are described in 80% of patients at the time of diagnosis.…”
Section: Methodssupporting
confidence: 48%
“…9,12 Paraproteinemias are associated with several different types of neuropathy. 13,14 Furthermore, drug treatment of Waldenstr€ om disease and multiple myeloma may involve the use of CIPN-causing medications (proteasome inhibitors, thalidomide, and related analogues), which can further complicate the determination of the etiology of the neuropathy. Bone marrow transplantation resulting in graft versus host disease can be associated with neuropathies such as Guillain-Barr e syndrome and CIDP.…”
Section: Approach To Peripheral Neuropathy In Patients With Cancermentioning
confidence: 99%
“…Direct neoplastic infiltration may occur in neurolymphomatosis, leukemia, and rarely carcinoma, and may mimic chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) . Paraproteinemias are associated with several different types of neuropathy . Furthermore, drug treatment of Waldenström disease and multiple myeloma may involve the use of CIPN‐causing medications (proteasome inhibitors, thalidomide, and related analogues), which can further complicate the determination of the etiology of the neuropathy.…”
Section: Approach To Peripheral Neuropathy In Patients With Cancermentioning
confidence: 99%